Literature DB >> 20118996

Mitochondria get a Parkin' ticket.

Philipp Wild1, Ivan Dikic.   

Abstract

Recent studies have revealed a prominent role of mitochondrial dysfunction in the development of one of the most common neurodegenerative disorders, Parkinson's disease. The ubiquitin ligase Parkin and the protein kinase PINK1, whose mutations are associated with Parkinson's disease, function in a pathway that links ubiquitylation with selective autophagy of damaged mitochondria.

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Year:  2010        PMID： 20118996     DOI： 10.1038/ncb0210-104

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  15 in total

1.  Ubiquitin tag for sperm mitochondria.

Authors:  P Sutovsky; R D Moreno; J Ramalho-Santos; T Dominko; C Simerly; G Schatten
Journal:  Nature       Date:  1999-11-25       Impact factor: 49.962

2.  Nix is a selective autophagy receptor for mitochondrial clearance.

Authors:  Ivana Novak; Vladimir Kirkin; David G McEwan; Ji Zhang; Philipp Wild; Alexis Rozenknop; Vladimir Rogov; Frank Löhr; Doris Popovic; Angelo Occhipinti; Andreas S Reichert; Janos Terzic; Volker Dötsch; Paul A Ney; Ivan Dikic
Journal:  EMBO Rep       Date:  2009-12-11       Impact factor: 8.807

3.  Mitochondria-anchored receptor Atg32 mediates degradation of mitochondria via selective autophagy.

Authors:  Koji Okamoto; Noriko Kondo-Okamoto; Yoshinori Ohsumi
Journal:  Dev Cell       Date:  2009-07       Impact factor: 12.270

4.  Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.

Authors:  T Kitada; S Asakawa; N Hattori; H Matsumine; Y Yamamura; S Minoshima; M Yokochi; Y Mizuno; N Shimizu
Journal:  Nature       Date:  1998-04-09       Impact factor: 49.962

5.  Lewy bodies.

Authors:  Clifford W Shults
Journal:  Proc Natl Acad Sci U S A       Date:  2006-01-31       Impact factor: 11.205

6.  PINK1-dependent recruitment of Parkin to mitochondria in mitophagy.

Authors:  Cristofol Vives-Bauza; Chun Zhou; Yong Huang; Mei Cui; Rosa L A de Vries; Jiho Kim; Jessica May; Maja Aleksandra Tocilescu; Wencheng Liu; Han Seok Ko; Jordi Magrané; Darren J Moore; Valina L Dawson; Regis Grailhe; Ted M Dawson; Chenjian Li; Kim Tieu; Serge Przedborski
Journal:  Proc Natl Acad Sci U S A       Date:  2009-12-04       Impact factor: 11.205

7.  Atg32 is a mitochondrial protein that confers selectivity during mitophagy.

Authors:  Tomotake Kanki; Ke Wang; Yang Cao; Misuzu Baba; Daniel J Klionsky
Journal:  Dev Cell       Date:  2009-07       Impact factor: 12.270

8.  PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1.

Authors:  Sven Geisler; Kira M Holmström; Diana Skujat; Fabienne C Fiesel; Oliver C Rothfuss; Philipp J Kahle; Wolfdieter Springer
Journal:  Nat Cell Biol       Date:  2010-01-24       Impact factor: 28.824

9.  Genome-wide and functional annotation of human E3 ubiquitin ligases identifies MULAN, a mitochondrial E3 that regulates the organelle's dynamics and signaling.

Authors:  Wei Li; Mario H Bengtson; Axel Ulbrich; Akio Matsuda; Venkateshwar A Reddy; Anthony Orth; Sumit K Chanda; Serge Batalov; Claudio A P Joazeiro
Journal:  PLoS One       Date:  2008-01-23       Impact factor: 3.240

10.  The PINK1/Parkin pathway regulates mitochondrial morphology.

Authors:  Angela C Poole; Ruth E Thomas; Laurie A Andrews; Heidi M McBride; Alexander J Whitworth; Leo J Pallanck
Journal:  Proc Natl Acad Sci U S A       Date:  2008-01-29       Impact factor: 11.205
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  26 in total

1.  Cell biology: Tagged tags engage disposal.

Authors:  Noriyuki Matsuda; Keiji Tanaka
Journal:  Nature       Date:  2015-08-12       Impact factor: 49.962

2.  Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) phosphorylation by protein kinase Cδ (PKCδ) inhibits mitochondria elimination by lysosomal-like structures following ischemia and reoxygenation-induced injury.

Authors:  Gouri Yogalingam; Sunhee Hwang; Julio C B Ferreira; Daria Mochly-Rosen
Journal:  J Biol Chem       Date:  2013-05-07       Impact factor: 5.157

3.  Parkin mediates beclin-dependent autophagic clearance of defective mitochondria and ubiquitinated Abeta in AD models.

Authors:  Preeti J Khandelwal; Alexander M Herman; Hyang-Sook Hoe; G William Rebeck; Charbel E-H Moussa
Journal:  Hum Mol Genet       Date:  2011-03-04       Impact factor: 6.150

Review 4.  Autophagy in tumorigenesis and energy metabolism: friend by day, foe by night.

Authors:  Robin Mathew; Eileen White
Journal:  Curr Opin Genet Dev       Date:  2011-01-20       Impact factor: 5.578

Review 5.  Role of autophagy in cancer prevention.

Authors:  Hsin-Yi Chen; Eileen White
Journal:  Cancer Prev Res (Phila)       Date:  2011-07

6.  GCN5-like protein 1 (GCN5L1) controls mitochondrial content through coordinated regulation of mitochondrial biogenesis and mitophagy.

Authors:  Iain Scott; Bradley R Webster; Carmen K Chan; Joshua U Okonkwo; Kim Han; Michael N Sack
Journal:  J Biol Chem       Date:  2013-12-19       Impact factor: 5.157

Review 7.  Activating Autophagy as a Therapeutic Strategy for Parkinson's Disease.

Authors:  Alan J Fowler; Charbel E-H Moussa
Journal:  CNS Drugs       Date:  2018-01       Impact factor: 5.749

Review 8.  Mitochondrial quality control in cardiac cells: Mechanisms and role in cardiac cell injury and disease.

Authors:  Farzaneh G Tahrir; Dianne Langford; Shohreh Amini; Taha Mohseni Ahooyi; Kamel Khalili
Journal:  J Cell Physiol       Date:  2018-11-11       Impact factor: 6.384

Review 9.  Emerging functions of the VCP/p97 AAA-ATPase in the ubiquitin system.

Authors:  Hemmo Meyer; Monika Bug; Sebastian Bremer
Journal:  Nat Cell Biol       Date:  2012-02-02       Impact factor: 28.824

Review 10.  Animal models of Parkinson's disease: vertebrate genetics.

Authors:  Yunjong Lee; Valina L Dawson; Ted M Dawson
Journal:  Cold Spring Harb Perspect Med       Date:  2012-10-01       Impact factor: 6.915
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