Literature DB >> 20117942

Longitudinal growth of the autologous vessels above and below the Gore-Tex graft after the extracardiac conduit Fontan procedure.

Yoshie Ochiai1, Yutaka Imoto, Masato Sakamoto, Akira Sese, Masaaki Tsukuda, Mamie Watanabe, Takuro Ohno, Kunitaka Joo.   

Abstract

OBJECTIVE: Reflecting excellent mid-term outcomes, extracardiac conduit Fontan procedure (ECFP) using Gore-Tex tube graft has been performed with increasing frequency in patients with functional single ventricle. Nevertheless, due to the lack of growth potential of the artificial conduit, the status of the venous pathway along with somatic growth is a continuing concern. In this study, we evaluated the longitudinal growth of the autologous vessels above and below the Gore-Tex graft used in the ECFP.
METHODS: This study included 34 patients who had completed cardiac catheterisations at 1 month and 5.1 years after the ECFP. The average age, weight and height at the ECFP were 3.8+/-2.5 years (1.8-12.7 years), 12.7+/-4.6 kg (7.4-33.0 kg) and 92.9+/-16.1cm (72.5-153.5 cm), respectively. We measured the vertical lengths of three different parts angiographically: the length between the confluence point of the innominate vein and the anastomotic site of the conduit to the pulmonary artery (SVC-C), the conduit vertical length (C) and the length between the confluence point of the hepatic vein and the conduit's anastomotic site to the inferior vena cava (IVC-C).
RESULTS: We have not observed stenosis or thrombus formation in the conduit or distortion of the conduit or pulmonary artery in any of the cases. No intervention or re-operation related to the extracardiac conduit was required, and laminar flow through the conduit was maintained with efficient Fontan haemodynamics. At 5.1 years after the ECFP, the average weight and height gain were 10.3+/-4.4 kg and 28.5+/-1.9 cm, respectively. The length of SVC-C, C and IVC-C were significantly increased as 124+/-15%, 106+/-7% and 132+/-24%, respectively, compared to the lengths at 1 month after the ECFP. The degree of increase in SVC-C and IVC-C was significantly larger than that in C.
CONCLUSIONS: Along with the patient's somatic growth, longitudinal growth of the autologous vessels above and below the Gore-Tex graft was demonstrated to compensate for the lack of growth potential of the artificial graft. Copyright 2009 European Association for Cardio-Thoracic Surgery. Published by Elsevier B.V. All rights reserved.

Entities:  

Mesh:

Substances:

Year:  2010        PMID: 20117942     DOI: 10.1016/j.ejcts.2009.12.010

Source DB:  PubMed          Journal:  Eur J Cardiothorac Surg        ISSN: 1010-7940            Impact factor:   4.191


  4 in total

Review 1.  Evaluating the Longevity of the Fontan Pathway.

Authors:  John M Kelly; Gabriel J M Mirhaidari; Yu-Chun Chang; Toshiharu Shinoka; Christopher K Breuer; Andrew R Yates; Kan N Hor
Journal:  Pediatr Cardiol       Date:  2020-11-08       Impact factor: 1.655

2.  Fontan pathway growth: a quantitative evaluation of lateral tunnel and extracardiac cavopulmonary connections using serial cardiac magnetic resonance.

Authors:  Maria Restrepo; Lucia Mirabella; Elaine Tang; Christopher M Haggerty; Reza H Khiabani; Francis Fynn-Thompson; Anne Marie Valente; Doff B McElhinney; Mark A Fogel; Ajit P Yoganathan
Journal:  Ann Thorac Surg       Date:  2014-01-18       Impact factor: 4.330

Review 3.  Antiplatelet versus anticoagulation therapy after extracardiac conduit Fontan: a systematic review and meta-analysis.

Authors:  Chiara Marrone; Gennaro Galasso; Raffaele Piccolo; Francesco de Leva; Rodolfo Paladini; Federico Piscione; Giuseppe Santoro
Journal:  Pediatr Cardiol       Date:  2010-10-22       Impact factor: 1.655

4.  Engineering Perspective on Cardiovascular Simulations of Fontan Hemodynamics: Where Do We Stand with a Look Towards Clinical Application.

Authors:  Zhenglun Alan Wei; Mark A Fogel
Journal:  Cardiovasc Eng Technol       Date:  2021-06-10       Impact factor: 2.495

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.