Literature DB >> 201163

Bradykinin action in the rat duodenum through the cyclic AMP system.

I Paegelow, S Reissmann, G Vietinghoff, W Römer, H Arold.   

Abstract

Activators of the adenylate cyclase or inhibitors of the cAMP-phosphodiesterase, respectively, potentiate the bradykinin-induced relaxation of the rat duodenum, whereas imidazole as a stimulator of the cAMP-phosphodiesterase reduces the relaxation. The experiments indicate a linkage between the adenylate cyclase system with the biological action of bradykinin on the rat duodenum. In contrast, no similar effect has been observed on the rat uterus.

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Year:  1977        PMID： 201163     DOI： 10.1007/bf01966851

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  21 in total

1.  Adenyl cylase. I. Distribution, preparation, and properties.

Authors:  E W SUTHERLAND; T W RALL; T MENON
Journal:  J Biol Chem       Date:  1962-04       Impact factor: 5.157

2.  Intracellular cyclic AMP level and intestinal smooth muscle relaxation.

Authors:  N Inatomi; I Takayanagi; M Uchida; K Takagi
Journal:  Eur J Pharmacol       Date:  1974-04       Impact factor: 4.432

3.  Role of cyclic AMP and Ca++ in metabolic and mechanical events in smooth muscle.

Authors:  R Andersson; L Lundholm; E Mohme-Lundholm; K Nilsson
Journal:  Adv Cyclic Nucleotide Res       Date:  1972

4.  Effect of catecholamines, histamine and oxyfedrine on isotonic contraction and cyclic AMP in the guinea-pig heart.

Authors:  W R Kukovetz; G Pöch; A Wurm
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1973       Impact factor: 3.000

5.  Cyclic AMP as a mediator of the relaxing action of papaverine, nitroglycerine, diazoxide and hydralazine in intestinal and vascular smooth muscle.

Authors:  R Andersson
Journal:  Acta Pharmacol Toxicol (Copenh)       Date:  1973

6.  Role of cyclic AMP and Ca ++ in mechanical and metabolic events in isometrically contracting vascular smooth muscle.

Authors:  R Andersson
Journal:  Acta Physiol Scand       Date:  1973-01

Review 7.  Cyclic AMP and drug action.

Authors:  B M Breckenridge
Journal:  Annu Rev Pharmacol       Date:  1970       Impact factor: 13.820

8.  Cardiostimulatory effects of cyclic 3',5'-adenosine monophosphate and its acylated derivatives.

Authors:  W R Kukovetz; G Pöch
Journal:  Naunyn Schmiedebergs Arch Pharmakol       Date:  1970

9.  Studies on the possible role of cyclic AMP in drug-induced coronary vasodilatation.

Authors:  G Pöch; W R Kukovetz
Journal:  Adv Cyclic Nucleotide Res       Date:  1972

10.  The effect of catecholamine depletion on the bradykinin-induced relaxation of isolated smooth muscle.

Authors:  J G Ufkes; C Van der Meer
Journal:  Eur J Pharmacol       Date:  1975-08       Impact factor: 4.432
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  2 in total

1.  Effects of methylprednisolone on exercise-induced increases of plasma levels of polymorphonuclear elastase and myeloperoxidase in man. Preliminary results.

Authors:  G Camus; J Pincemail; G Deby-Dupont; C Deby; A Juchmès-Ferir; M Lamy
Journal:  Mediators Inflamm       Date:  1993       Impact factor: 4.711

2.  Bradykinin receptors in intestinal smooth muscles and their post-receptor events related to calcium.

Authors:  Y Oztürk; V M Altan; N Yıdızoğlu-Arı; O Altınkurt
Journal:  Mediators Inflamm       Date:  1993       Impact factor: 4.711
  2 in total

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