| Literature DB >> 20114021 |
Abstract
Underhill and colleagues (Shimada et al., 2010) provide evidence for an intriguing link between the activity of lysozyme in the phagosome and activation of the Nlrp3 inflammasome, a cytosolic regulator of inflammation and cytokine production. The authors show that resistance to lysozyme allows Staphylococcus aureus to evade Nlrp3 activation. 2010 Elsevier Inc. All rights reserved.Entities:
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Year: 2010 PMID: 20114021 DOI: 10.1016/j.chom.2009.12.011
Source DB: PubMed Journal: Cell Host Microbe ISSN: 1931-3128 Impact factor: 21.023