Literature DB >> 20112128

10-Hydroxycamptothecin produced by a new endophytic Xylaria sp., M20, from Camptotheca acuminata.

Kaihui Liu1, Xiaowei Ding, Baiwan Deng, Wenqiang Chen.   

Abstract

A new 10-hydroxycamptothecin (HCPT)-producing fungus was isolated from Camptotheca acuminata. The strain was classified as a Xylaria sp. based on the internal transcribed spacer and 18S rDNA gene analysis. All elicitors tested, except methyl jasmonate, increased HCPT production in submerged culture. The maximum yield was 5.4 mg HCPT/l(-1), when salicylic acid was added at 0.1 mM to the culture medium.

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Year:  2010        PMID： 20112128     DOI： 10.1007/s10529-010-0201-4

Source DB:  PubMed          Journal:  Biotechnol Lett        ISSN： 0141-5492            Impact factor:   2.461


  8 in total

1.  Isolation and characterization of Paenibacillus polymyxa LY214, a camptothecin-producing endophytic bacterium from Camptotheca acuminata.

Authors:  Xiang Pu; Fei Chen; Yun Yang; Xixing Qu; Guolin Zhang; Yinggang Luo
Journal:  J Ind Microbiol Biotechnol       Date:  2015-06-28       Impact factor: 3.346

2.  Bioprocesses optimization and anticancer activity of camptothecin from Aspergillus flavus, an endophyte of in vitro cultured Astragalus fruticosus.

Authors:  Ashraf S A El-Sayed; Rawia A Zayed; Ashraf F El-Baz; Wafaa M Ismaeil
Journal:  Mol Biol Rep       Date:  2022-03-21       Impact factor: 2.742

3.  De novo transcriptome assembly and characterization of the 10-hydroxycamptothecin-producing Xylaria sp. M71 following salicylic acid treatment.

Authors:  Xiaowei Ding; Kaihui Liu; Yonggui Zhang; Feihu Liu
Journal:  J Microbiol       Date:  2017-10-27       Impact factor: 3.422

4.  The use of endophytes to obtain bioactive compounds and their application in biotransformation process.

Authors:  Mariana Recco Pimentel; Gustavo Molina; Ana Paula Dionísio; Mário Roberto Maróstica Junior; Gláucia Maria Pastore
Journal:  Biotechnol Res Int       Date:  2010-09-26

Review 5.  Fungal Endophytes as Efficient Sources of Plant-Derived Bioactive Compounds and Their Prospective Applications in Natural Product Drug Discovery: Insights, Avenues, and Challenges.

Authors:  Archana Singh; Dheeraj K Singh; Ravindra N Kharwar; James F White; Surendra K Gond
Journal:  Microorganisms       Date:  2021-01-19

Review 6.  Identification and Bioactivities of Secondary Metabolites Derived from Endophytic Fungi Isolated from Ethnomedicinal Plants of Tujia in Hubei Province: A Review.

Authors:  Ke Ye; Hong-Lian Ai; Ji-Kai Liu
Journal:  Nat Prod Bioprospect       Date:  2021-01-20

Review 7.  Endophytic Fungal Terpenoids: Natural Role and Bioactivities.

Authors:  Juan M Galindo-Solís; Francisco J Fernández
Journal:  Microorganisms       Date:  2022-02-01

8.  Diversity and taxonomy of endophytic xylariaceous fungi from medicinal plants of Dendrobium (Orchidaceae).

Authors:  Juan Chen; Li-Chun Zhang; Yong-Mei Xing; Yun-Qiang Wang; Xiao-Ke Xing; Da-Wei Zhang; Han-Qiao Liang; Shun-Xing Guo
Journal:  PLoS One       Date:  2013-03-05       Impact factor: 3.240
  8 in total

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