Literature DB >> 20111975

The synergistic efficacy of adalimumab and pamidronate in a patient with ankylosing spondylitis.

Gleb Slobodin1, Itzhak Rosner, Doron Rimar, Nina Boulman, Michael Rozenbaum, Majed Odeh.   

Abstract

A patient with ankylosing spondylitis, after demonstrating incomplete clinical response to adalimumab, received three monthly infusions of pamidronate along with continuing TNF-alpha blockade. Complete disappearance of the back pain was reported after the second pamidronate infusion. The perspectives of the combination therapy with TNF-alpha inhibitor and pamidronate are discussed.

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Year:  2010        PMID： 20111975     DOI： 10.1007/s10067-010-1378-6

Source DB:  PubMed          Journal:  Clin Rheumatol        ISSN： 0770-3198            Impact factor:   2.980


  5 in total

Review 1.  A systematic MEDLINE analysis of therapeutic approaches in ankylosing spondylitis.

Authors:  L Goh; A Samanta
Journal:  Rheumatol Int       Date:  2009-06-28       Impact factor: 2.631

2.  Efficacy and safety of adalimumab in patients with ankylosing spondylitis: results of a multicenter, randomized, double-blind, placebo-controlled trial.

Authors:  Désirée van der Heijde; Alan Kivitz; Michael H Schiff; Joachim Sieper; Ben A C Dijkmans; Jürgen Braun; Maxime Dougados; John D Reveille; Robert L Wong; Hartmut Kupper; John C Davis
Journal:  Arthritis Rheum       Date:  2006-07

3.  A six-month randomized, controlled, double-blind, dose-response comparison of intravenous pamidronate (60 mg versus 10 mg) in the treatment of nonsteroidal antiinflammatory drug-refractory ankylosing spondylitis.

Authors:  Walter P Maksymowych; Gian S Jhangri; Avril A Fitzgerald; Sharon LeClercq; Peter Chiu; Alex Yan; Kenneth J Skeith; Stephen L Aaron; Joanne Homik; Paul Davis; Dale Sholter; Anthony S Russell
Journal:  Arthritis Rheum       Date:  2002-03

4.  Efficacy and safety of infliximab in patients with ankylosing spondylitis: results of a randomized, placebo-controlled trial (ASSERT).

Authors:  Désirée van der Heijde; Ben Dijkmans; Piet Geusens; Joachim Sieper; Kimberly DeWoody; Paul Williamson; Jürgen Braun
Journal:  Arthritis Rheum       Date:  2005-02

5.  Six-month results of a double-blind, placebo-controlled trial of etanercept treatment in patients with active ankylosing spondylitis.

Authors:  J Brandt; A Khariouzov; J Listing; H Haibel; H Sörensen; L Grassnickel; M Rudwaleit; J Sieper; J Braun
Journal:  Arthritis Rheum       Date:  2003-06
  5 in total

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