CONTEXT: Little is known about the acute effects of resistance exercise on insulin sensitivity in people with type 1 diabetes. DESIGN: Repeated-measures design with 2 independent variables: group (exercise and nonexercise control) and time (preexercise and 12 and 36 h postexercise). SETTING: General Clinical Research Center, Temple University Hospital, Philadelphia, PA. PATIENTS: 14 physically active subjects (11 men and 3 women) with type 1 diabetes. INTERVENTION: The exercise group completed 5 sets of 6 repetitions of strenuous (80% 1-RM) quadriceps and hamstring exercises while the control group performed only activities of daily living. MAIN OUTCOME MEASURES: Insulin sensitivity was assessed with the euglycemic-hyperinsulinemic-clamp technique preexercise and 12 and 36 h postexercise. RESULTS:Insulin-sensitivity values were not significantly different between the exercise and control groups (P = .92) or over time (P = .67). CONCLUSIONS: A single bout of strenuous resistance exercise does not alter insulin sensitivity in people with type 1 diabetes.
RCT Entities:
CONTEXT: Little is known about the acute effects of resistance exercise on insulin sensitivity in people with type 1 diabetes. DESIGN: Repeated-measures design with 2 independent variables: group (exercise and nonexercise control) and time (preexercise and 12 and 36 h postexercise). SETTING: General Clinical Research Center, Temple University Hospital, Philadelphia, PA. PATIENTS: 14 physically active subjects (11 men and 3 women) with type 1 diabetes. INTERVENTION: The exercise group completed 5 sets of 6 repetitions of strenuous (80% 1-RM) quadriceps and hamstring exercises while the control group performed only activities of daily living. MAIN OUTCOME MEASURES: Insulin sensitivity was assessed with the euglycemic-hyperinsulinemic-clamp technique preexercise and 12 and 36 h postexercise. RESULTS:Insulin-sensitivity values were not significantly different between the exercise and control groups (P = .92) or over time (P = .67). CONCLUSIONS: A single bout of strenuous resistance exercise does not alter insulin sensitivity in people with type 1 diabetes.
Authors: Jane E Yardley; Glen P Kenny; Bruce A Perkins; Michael C Riddell; Janine Malcolm; Pierre Boulay; Farah Khandwala; Ronald J Sigal Journal: Diabetes Care Date: 2012-02-28 Impact factor: 19.112
Authors: Olivia McCarthy; Othmar Moser; Max L Eckstein; Rachel Deere; Steve C Bain; Jason Pitt; Richard M Bracken Journal: Front Endocrinol (Lausanne) Date: 2019-08-02 Impact factor: 5.555