Literature DB >> 2010788

The effectiveness of the hair-restorer "Dabao" in males with alopecia androgenetica. A clinical experiment.

A G Kessels1, R L Cardynaals, R L Borger, M J Go, J C Lambers, J A Knottnerus, P G Knipschild.   

Abstract

In a randomized, double-blind trial the effectiveness of 6 months' use of a Chinese herb extract (Dabao) as a hair-restorer was studied on 396 males with alopecia androgenetica. The effect was evaluated by nonvellus hair counts, participants' opinions and a panel's judgement of a photo-report. Twenty-three participants withdrew prematurely from the study. In both the Dabao and placebo groups an increase in the amount of hair was observed; 133 and 109 hairs on a 5 cm2 marked area, a difference of 24 hairs (p = 0.03, one-sided). Participants as well as the panel reached a similar conclusion. Regarding cosmetic effect, 42% of the participants in the Dabao group and 37% in the placebo group reported positive results. The average panel score for the cosmetic result on a scale of -10 to +10 was 0.46 in the Dabao and 0.21 in the placebo group, a difference of 0.24 (p = 0.04, one-sided). It appears from our study that, although the cosmetic effect over 6 months is modest, Dabao does have a certain effect on the growth of nonvellus hair.

Entities:  

Mesh:

Substances:

Year:  1991        PMID: 2010788     DOI: 10.1016/0895-4356(91)90083-l

Source DB:  PubMed          Journal:  J Clin Epidemiol        ISSN: 0895-4356            Impact factor:   6.437


  4 in total

1.  Trials of homeopathy.

Authors:  J Kleijnen; P Knipschild; G ter Riet
Journal:  BMJ       Date:  1991-04-20

Review 2.  The role of plant-derived drugs and herbal medicines in healthcare.

Authors:  P A De Smet
Journal:  Drugs       Date:  1997-12       Impact factor: 9.546

3.  An Herbal Extract Combination (Biochanin A, Acetyl tetrapeptide-3, and Ginseng Extracts) versus 3% Minoxidil Solution for the Treatment of Androgenetic Alopecia: A 24-week, Prospective, Randomized, Triple-blind, Controlled Trial.

Authors:  Suparuj Lueangarun; Ratchathorn Panchaprateep
Journal:  J Clin Aesthet Dermatol       Date:  2020-10-01

4.  Exploring the combination and modular characteristics of herbs for alopecia treatment in traditional Chinese medicine: an association rule mining and network analysis study.

Authors:  Jungtae Leem; Wonmo Jung; Yohwan Kim; Bonghyun Kim; Kyuseok Kim
Journal:  BMC Complement Altern Med       Date:  2018-07-04       Impact factor: 3.659

  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.