| Literature DB >> 20107759 |
O Bachmann1, F Länger, J Rademacher.
Abstract
Pulmonary disease is a rare complication of inflammatory bowel disease. Airway inflammation, interstitial lung disease and several other manifestations have been described, and typical symptoms are productive cough, chest pain, and progressive dyspnea. Due to the frequency of preceding pulmonary disease and the common temporal dissociation regarding intestinal disease, pulmonary manifestations of inflammatory bowel disease are at high risk of being overlooked. If suspected, early work-up including CT scan and bronchoscopy should be initiated, since the natural course often involves rapidly progressive lung damage. The best therapeutic results have been obtained with topic and systemic steroids, while classic immunosuppressants are commonly not efficacious. Several case reports describe a beneficial effect of infliximab.Entities:
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Year: 2010 PMID: 20107759 DOI: 10.1007/s00108-009-2504-x
Source DB: PubMed Journal: Internist (Berl) ISSN: 0020-9554 Impact factor: 0.743