Literature DB >> 20107217

Vaccine-acquired rotavirus in infants with severe combined immunodeficiency.

Niraj C Patel1, Paula M Hertel, Mary K Estes, Maite de la Morena, Ann M Petru, Lenora M Noroski, Paula A Revell, I Celine Hanson, Mary E Paul, Howard M Rosenblatt, Stuart L Abramson.   

Abstract

Live pentavalent human-bovine reassortant rotavirus vaccine is recommended in the United States for routine immunization of infants. We describe three infants, two with failure to thrive, who had dehydration and diarrhea within 1 month after their first or second rotavirus immunization and subsequently received a diagnosis of severe combined immunodeficiency. Rotavirus was detected, by means of reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay, in stool specimens obtained from all three infants, and gene-sequence analysis revealed the presence of vaccine rotavirus. These infections raise concerns regarding the safety of rotavirus vaccine in severely immunocompromised patients. 2010 Massachusetts Medical Society

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Year:  2010        PMID： 20107217      PMCID： PMC4103739          DOI： 10.1056/NEJMoa0904485

Source DB:  PubMed          Journal:  N Engl J Med        ISSN： 0028-4793            Impact factor:   91.245


  22 in total

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7.  Lymphocyte subsets in healthy children from birth through 18 years of age: the Pediatric AIDS Clinical Trials Group P1009 study.

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  60 in total

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Authors:  Mercedes C Amado
Journal:  Mo Med       Date:  2011 Sep-Oct

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Authors:  Bingxin Zhao; Xiaoxia Pan; Yumei Teng; Wenyue Xia; Jing Wang; Yuling Wen; Yuanding Chen
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3.  Neonatal screening for severe combined immunodeficiency.

Authors:  Jennifer M Puck
Journal:  Curr Opin Pediatr       Date:  2011-12       Impact factor: 2.856

Review 4.  The long quest for neonatal screening for severe combined immunodeficiency.

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Journal:  J Allergy Clin Immunol       Date:  2012-01-24       Impact factor: 10.793

5.  Laboratory technology for population-based screening for severe combined immunodeficiency in neonates: the winner is T-cell receptor excision circles.

Authors:  Jennifer M Puck
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6.  Molecular diagnosis of severe combined immunodeficiency--identification of IL2RG, JAK3, IL7R, DCLRE1C, RAG1, and RAG2 mutations in a cohort of Chinese and Southeast Asian children.

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Journal:  J Clin Immunol       Date:  2010-12-24       Impact factor: 8.317

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Authors:  Alice Chan; Christopher Scalchunes; Marcia Boyle; Jennifer M Puck
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Authors:  Ulrich Desselberger; Hans-Iko Huppertz
Journal:  J Infect Dis       Date:  2011-01-15       Impact factor: 5.226

Review 9.  Evaluation of vaccines against enteric infections: a clinical and public health research agenda for developing countries.

Authors:  John Clemens
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2011-10-12       Impact factor: 6.237

10.  Safety and immunogenicity of a live attenuated pentavalent rotavirus vaccine in HIV-exposed infants with or without HIV infection in Africa.

Authors:  Myron J Levin; Jane C Lindsey; Susan S Kaplan; Werner Schimana; Jody Lawrence; Monica M McNeal; Mutsa Bwakura-Dangarembizi; Anthony Ogwu; Evans M Mpabalwani; Paul Sato; George Siberry; Margaret Nelson; Darcy Hille; Geoffrey A Weinberg; Adriana Weinberg
Journal:  AIDS       Date:  2017-01-02       Impact factor: 4.177
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