| Literature DB >> 20107008 |
An Li1, Quan Yuan, Zhiyin Huang, Jian Fan, Ruyi Guo, Bin Lou, Qin Zheng, Shengxiang Ge, Yixin Chen, Zhijun Su, Anthony E T Yeo, Yu Chen, Jun Zhang, Ningshao Xia.
Abstract
A novel diagnostic immunoassay testing procedure for hepatitis B virus core antibody (anti-HBc) using homogeneous purified full-length hepatitis B virus core antigen (HBcAg) capsids obtained from Escherichia coli was compared with Abbott Architect anti-HBc chemiluminescent microparticle immunoassay (CMIA; indirect method) against a library of specimens. A monoclonal anti-HBc neutralization confirmatory assay was then used to determine the degree of discordance between specimens. The new assay was found to be superior in both sensitivity and specificity.Entities:
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Year: 2010 PMID: 20107008 PMCID: PMC2837963 DOI: 10.1128/CVI.00457-09
Source DB: PubMed Journal: Clin Vaccine Immunol ISSN: 1556-679X