Frank Doyle1, Ronán Conroy, Hannah McGee, Mary Delaney. 1. Department of Psychology, Division of Population Health Sciences, Royal College of Surgeons in Ireland, Dublin 2, Ireland. fdoyle4@rcsi.ie
Abstract
OBJECTIVE: To determine which particular depressive symptom scales, derived from three scales, predicted poorer prognosis in persons with acute coronary syndrome (ACS). METHODS: Hospitalized ACS patients (n=408) completed questionnaires (depression, vital exhaustion). Mokken scaling derived unidimensional scales. Major cardiac events (cardiac mortality, ACS, unplanned revascularization) were assessed at median 67 weeks post event. RESULTS: Only depressive symptoms of fatigue-sadness predicted prognosis in univariate (hazard ratio [HR]=1.8, 95% CI 1.1-3.0, P=.025) and multivariate analysis (HR=1.8, 95% CI 1.1-2.9, P=.025). Symptoms of anhedonia (HR=1.6, 95% CI 0.9-2.8, P=.102) and depressive cognitions (HR=1.3, 95% CI 0.7-2.2, P=.402) did not. CONCLUSION: Symptoms of fatigue-sadness, but not other symptoms, were associated with increased risk of major cardiac events. Depression should be considered as a multidimensional, rather than a unidimensional, entity when designing interventions. 2010 Elsevier Inc. All rights reserved.
OBJECTIVE: To determine which particular depressive symptom scales, derived from three scales, predicted poorer prognosis in persons with acute coronary syndrome (ACS). METHODS: Hospitalized ACS patients (n=408) completed questionnaires (depression, vital exhaustion). Mokken scaling derived unidimensional scales. Major cardiac events (cardiac mortality, ACS, unplanned revascularization) were assessed at median 67 weeks post event. RESULTS: Only depressive symptoms of fatigue-sadness predicted prognosis in univariate (hazard ratio [HR]=1.8, 95% CI 1.1-3.0, P=.025) and multivariate analysis (HR=1.8, 95% CI 1.1-2.9, P=.025). Symptoms of anhedonia (HR=1.6, 95% CI 0.9-2.8, P=.102) and depressive cognitions (HR=1.3, 95% CI 0.7-2.2, P=.402) did not. CONCLUSION: Symptoms of fatigue-sadness, but not other symptoms, were associated with increased risk of major cardiac events. Depression should be considered as a multidimensional, rather than a unidimensional, entity when designing interventions. 2010 Elsevier Inc. All rights reserved.
Authors: Diana A Chirinos; Indira Gurubhagavatula; Preston Broderick; Julio A Chirinos; Karen Teff; Thomas Wadden; Greg Maislin; Hassam Saif; Jesse Chittams; Caitlin Cassidy; Alexandra L Hanlon; Allan I Pack Journal: J Behav Med Date: 2017-06-21
Authors: Diana A Chirinos; Ronald Goldberg; Marc Gellman; Armando J Mendez; Miriam Gutt; Judith R McCalla; Maria M Llabre; Neil Schneiderman Journal: Ann Behav Med Date: 2013-08