AIM: To test the hypothesis that the shape and length of Barrett's epithelium are associated with prevalence of erosive esophagitis. METHODS: A total study population comprised 869 patients who underwent endoscopy during a health checkup at our hospital. The presence and extent of Barrett's epithelium were diagnosed based on the Prague C & M Criteria. We originally classified cases of Barrett's epithelium into two types based on its shape, namely, flame-like and lotus-like Barrett's epithelium, and into two groups based on its length, its C extent < 2 cm, and > or = 2 cm. Correlation of shape and length of Barrett's epithelium with erosive esophagitis was examined. RESULTS: Barrett's epithelium was diagnosed in 374 cases (43%). Most of these were diagnosed as short-segment Barrett's epithelium. The prevalence of erosive esophagitis was significantly higher in subjects with flame-like than lotus-like Barrett's epithelium, and in those with a C extent of > or = 2 cm than < 2 cm. CONCLUSION: Flame-like rather than lotus-like Barrett's epithelium, and Barrett's epithelium with a longer segment were more strongly associated with erosive esophagitis.
AIM: To test the hypothesis that the shape and length of Barrett's epithelium are associated with prevalence of erosive esophagitis. METHODS: A total study population comprised 869 patients who underwent endoscopy during a health checkup at our hospital. The presence and extent of Barrett's epithelium were diagnosed based on the Prague C & M Criteria. We originally classified cases of Barrett's epithelium into two types based on its shape, namely, flame-like and lotus-like Barrett's epithelium, and into two groups based on its length, its C extent < 2 cm, and > or = 2 cm. Correlation of shape and length of Barrett's epithelium with erosive esophagitis was examined. RESULTS: Barrett's epithelium was diagnosed in 374 cases (43%). Most of these were diagnosed as short-segment Barrett's epithelium. The prevalence of erosive esophagitis was significantly higher in subjects with flame-like than lotus-like Barrett's epithelium, and in those with a C extent of > or = 2 cm than < 2 cm. CONCLUSION: Flame-like rather than lotus-like Barrett's epithelium, and Barrett's epithelium with a longer segment were more strongly associated with erosive esophagitis.
Authors: T Akiyama; M Inamori; K Akimoto; H Iida; H Mawatari; H Endo; T Ikeda; Y Nozaki; K Yoneda; Y Sakamoto; K Fujita; M Yoneda; H Takahashi; S Hirokawa; A Goto; Y Abe; H Kirikoshi; N Kobayashi; K Kubota; S Saito; A Nakajima Journal: Dig Dis Sci Date: 2008-11-12 Impact factor: 3.199
Authors: D C Farrow; T L Vaughan; C Sweeney; M D Gammon; W H Chow; H A Risch; J L Stanford; P D Hansten; S T Mayne; J B Schoenberg; H Rotterdam; H Ahsan; A B West; R Dubrow; J F Fraumeni; W J Blot Journal: Cancer Causes Control Date: 2000-03 Impact factor: 2.506
Authors: Chris Tselepis; Ian Perry; Chris Dawson; Rob Hardy; S Jane Darnton; Chris McConkey; Rob C Stuart; Nick Wright; Rebecca Harrison; Janusz Antoni Z Jankowski Journal: Oncogene Date: 2002-09-05 Impact factor: 9.867