C-H Lai1, H-F Tseng. 1. Department of Neurology, Changhua Christian Hospital, Changhua, Taiwan.
Abstract
BACKGROUND: The purpose of the study is to investigate the epidemiology and medical expenses of Wilson's disease in Taiwan. METHODS: Cases of Wilson's disease were identified from the National Health Insurance Research Database with corresponding International Classification of Diseases, Ninth Revision (ICD-9) code 275.1 from January 2000 to December 2005. Age and sex-specific incidences were estimated by dividing the incidence number by population data obtained from the Department of Statistics, Ministry of the Interior. RESULTS: During the study period, 495 cases of Wilson's disease were identified. The male to female ratio was 1.28. The average annual incidence rate was 0.27 per 100,000, and the incidence rate peaked in the age group of 15-19 years. Most cases were juvenile and young adults. The prevalence increased steadily during the study period. Cirrhosis of the liver was the most common co-existing condition. CONCLUSIONS: This is the first population-based epidemiologic study of Wilson's disease in Taiwan. Because of the effective and affordable treatment, the prevalence of Wilson's disease in Taiwan is expected to increase continuously.
BACKGROUND: The purpose of the study is to investigate the epidemiology and medical expenses of Wilson's disease in Taiwan. METHODS: Cases of Wilson's disease were identified from the National Health Insurance Research Database with corresponding International Classification of Diseases, Ninth Revision (ICD-9) code 275.1 from January 2000 to December 2005. Age and sex-specific incidences were estimated by dividing the incidence number by population data obtained from the Department of Statistics, Ministry of the Interior. RESULTS: During the study period, 495 cases of Wilson's disease were identified. The male to female ratio was 1.28. The average annual incidence rate was 0.27 per 100,000, and the incidence rate peaked in the age group of 15-19 years. Most cases were juvenile and young adults. The prevalence increased steadily during the study period. Cirrhosis of the liver was the most common co-existing condition. CONCLUSIONS: This is the first population-based epidemiologic study of Wilson's disease in Taiwan. Because of the effective and affordable treatment, the prevalence of Wilson's disease in Taiwan is expected to increase continuously.
Authors: Eun Ju Choe; Jong Won Choi; Minjin Kang; Yong Kang Lee; Han Ho Jeon; Byung Kyu Park; Sun Young Won; Yong Suk Cho; Jeong Hun Seo; Chun Kyon Lee; Jae Bock Chung Journal: Sci Rep Date: 2020-08-20 Impact factor: 4.379
Authors: Pramudi Wijayasiri; Jatinder Hayre; Edward S Nicholson; Philip Kaye; Emilie A Wilkes; Jonathan Evans; Guruprasad P Aithal; Gabriela Jones; Fiona Pearce; Aloysious D Aravinthan Journal: JHEP Rep Date: 2021-07-07