Literature DB >> 20099458

Biological activities of crude extracts and chemical constituents of Bael, Aegle marmelos (L.) Corr.

Pallab Maity1, Dhananjay Hansda, Uday Bandyopadhyay, Dipak Kumar Mishra.   

Abstract

Bael (Aegle marmelos (L.) Corr.) is an important medicinal plant of India. Leaves, fruits, stem and roots of A. marmelos have been used in ethno medicine to exploit its' medicinal properties including astringent, antidiarrheal antidysenteric, demulcent, antipyretic and anti-inflammatory activities. Compounds purified from bael have been proven to be biologically active against several major diseases including cancer, diabetes and cardiovascular diseases. Preclinical studies indicate the therapeutic potential of crude extracts of A. marmelos in the treatment of many microbial diseases, diabetes and gastric ulcer. This review covers the biological activities of some isolated chemical constituents of A. marmelos and preclinical studies on some crude extracts and pure compounds to explore novel bioactive compounds for therapeutic application.

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Year:  2009        PMID: 20099458

Source DB:  PubMed          Journal:  Indian J Exp Biol        ISSN: 0019-5189            Impact factor:   0.818


  24 in total

1.  Semisynthetic studies identify mitochondria poisons from botanical dietary supplements--geranyloxycoumarins from Aegle marmelos.

Authors:  Jun Li; Fakhri Mahdi; Lin Du; Mika B Jekabsons; Yu-Dong Zhou; Dale G Nagle
Journal:  Bioorg Med Chem       Date:  2013-02-04       Impact factor: 3.641

2.  Identification of novel anti-inflammatory agents from Ayurvedic medicine for prevention of chronic diseases: "reverse pharmacology" and "bedside to bench" approach.

Authors:  Bharat B Aggarwal; Sahdeo Prasad; Simone Reuter; Ramaswamy Kannappan; Vivek R Yadev; Byoungduck Park; Ji Hye Kim; Subash C Gupta; Kanokkarn Phromnoi; Chitra Sundaram; Seema Prasad; Madan M Chaturvedi; Bokyung Sung
Journal:  Curr Drug Targets       Date:  2011-10       Impact factor: 3.465

3.  Mitochondrial respiration inhibitors suppress protein translation and hypoxic signaling via the hyperphosphorylation and inactivation of translation initiation factor eIF2α and elongation factor eEF2.

Authors:  Jun Li; Fakhri Mahdi; Lin Du; Sandipan Datta; Dale G Nagle; Yu-Dong Zhou
Journal:  J Nat Prod       Date:  2011-08-29       Impact factor: 4.050

4.  Aegle marmelos differentially affects hepatic markers of glycolysis, insulin signalling pathway, hypoxia, and inflammation in HepG2 cells grown in fructose versus glucose-rich environment.

Authors:  H Aggarwal; J Nair; P Sharma; R Sehgal; U Naeem; P Rajora; R Mathur
Journal:  Mol Cell Biochem       Date:  2017-08-01       Impact factor: 3.396

5.  Evaluation of protective effect of Aegle marmelos Corr. in an animal model of chronic fatigue syndrome.

Authors:  Vanphawng Lalremruta; Gurunath S Prasanna
Journal:  Indian J Pharmacol       Date:  2012-05       Impact factor: 1.200

6.  In Silico Exploration of Phytoconstituents From Phyllanthus emblica and Aegle marmelos as Potential Therapeutics Against SARS-CoV-2 RdRp.

Authors:  Khushboo Pandey; Kiran Bharat Lokhande; K Venkateswara Swamy; Shuchi Nagar; Manjusha Dake
Journal:  Bioinform Biol Insights       Date:  2021-06-24

7.  Antifertility activity of methanolic bark extract of Aegle marmelos (l.) in male wistar rats.

Authors:  Shyam S Agrawal; Ashok Kumar; Sumeet Gullaiya; Vishal Dubey; Ashish Nagar; Poonam Tiwari; Parul Dhar; Varun Singh
Journal:  Daru       Date:  2012-12-13       Impact factor: 3.117

8.  Aegle marmelos fruit extract attenuates isoproterenol-induced oxidative stress in rats.

Authors:  Gadham Setty Saayi Krushna; Mohammed Abdul Kareem; Vaddi Damodara Reddy; Pannuru Padmavathi; Shaik Althaf Hussain; Lakshmi Devi Kodidhela
Journal:  J Clin Biochem Nutr       Date:  2011-12-14       Impact factor: 3.114

9.  Umbelliferone β-D-galactopyranoside from Aegle marmelos (L.) corr. an ethnomedicinal plant with antidiabetic, antihyperlipidemic and antioxidative activity.

Authors:  Vikas Kumar; Danish Ahmed; Amita Verma; Firoz Anwar; Mohammed Ali; Mohd Mujeeb
Journal:  BMC Complement Altern Med       Date:  2013-10-20       Impact factor: 3.659

10.  Gene set enrichment analysis of PPAR-γ regulators from Murraya odorata Blanco.

Authors:  Ekta Kotharkar; Shailaja Nare; Prarambh Sr Dwivedi; V P Rasal; Pukar Khanal
Journal:  J Diabetes Metab Disord       Date:  2021-02-17
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