Literature DB >> 20099230

Corneal chrysiasis: in vivo confocal microscopy analysis.

Iacopo Paladini1, Ugo Menchini, Rita Mencucci.   

Abstract

PURPOSE: To describe the in vivo confocal microscopy corneal findings in a patient treated with gold sodium thiomalate.
METHODS: A woman with rheumatoid arthritis who had been treated with gold sodium thiomalate for 32 years came to our center for an ophthalmologic examination about 5 years ago. Besides visual acuity, the examination included slit-lamp biomicroscopy, intraocular pressure, and funduscopy. Confocal microscopy was performed using Confoscan 4 (Nidek Technologies, Padova, Italy) with a 40x lens.
RESULTS: Every layer of the cornea is affected by gold deposits with high reflectivity, especially in the anterior stroma, where they have a larger dimension.
CONCLUSIONS: Corneal chrysiasis can be evaluated by confocal microscopy, giving information on corneal metabolism and physiology.

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Year:  2010        PMID: 20099230     DOI: 10.1177/112067211002000421

Source DB:  PubMed          Journal:  Eur J Ophthalmol        ISSN: 1120-6721            Impact factor:   2.597


  3 in total

Review 1.  Ocular toxicity from systemically administered xenobiotics.

Authors:  Mitan R Gokulgandhi; Aswani Dutt Vadlapudi; Ashim K Mitra
Journal:  Expert Opin Drug Metab Toxicol       Date:  2012-07-18       Impact factor: 4.481

Review 2.  Drug-induced corneal deposits: an up-to-date review.

Authors:  Jean-Yves Sahyoun; Saama Sabeti; Marie-Claude Robert
Journal:  BMJ Open Ophthalmol       Date:  2022-03-25

3.  In vivo confocal microscopy in chloroquine-induced keratopathy.

Authors:  Iacopo Paladini; Ugo Menchini; Rita Mencucci
Journal:  Middle East Afr J Ophthalmol       Date:  2013 Jan-Mar
  3 in total

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