Literature DB >> 20098194

Radiation-induced leiomyosarcoma of the maxillofacial region: facial reconstruction with implant-retained prosthesis.

Secil Karakoca1, Cemal Aydin, Handan Yilmaz, Bilge Turhan Bal.   

Abstract

Radiation-induced sarcoma represents an exceptional rarity in the head and neck region. The treatment is surgical excision with negative margins and follow-up. After surgery, reconstruction of the defects can be accomplished either surgically or prosthetically. Implant-retained maxillofacial prostheses may offer an acceptable solution. In this report, a large facial defect resulting from radiation-induced leiomyosarcoma was reconstructed with implant-retained prosthesis. A patient with a large facial defect resulting from tumor surgery presented for reconstructive treatment. The primary tumor was fibrous histiosarcoma. Four years after the patient was treated with surgical resection and subsequent irradiation, leiomyosarcoma was diagnosed in the defect site. Leiomyosarcoma was treated with complete surgical resection, and the defect was reconstructed with implant-retained prosthesis. The patient was evaluated every 6 months. Implants provided secure retention to the prosthesis. The patient was satisfied with the appearance of the prosthesis. At 12 months' examination, functioning implants were successful; however, color fade of the prosthesis was observed. Radiation-induced leiomyosarcoma, which is an uncommon tumor in the head and neck region, was treated by means of large surgical resection. Implant-retained prosthetic rehabilitation of the patient resulted in acceptable functional and cosmetic results, and the patient has resumed social activities.

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Year:  2010        PMID: 20098194     DOI: 10.1097/SCS.0b013e3181c5a392

Source DB:  PubMed          Journal:  J Craniofac Surg        ISSN: 1049-2275            Impact factor:   1.046


  2 in total

1.  Leiomyosarcomas of the oral cavity: report of a radiation-associated and a metastatic case.

Authors:  Rebeca Souza Azevedo; Fábio Ramôa Pires; Adriele Ferreira Gouvêa; Márcio Ajudarte Lopes; Jacks Jorge
Journal:  Oral Maxillofac Surg       Date:  2011-09-27

Review 2.  Radiation-Induced Sarcomas of the Head and Neck: A Systematic Review.

Authors:  Andrés Coca-Pelaz; Antti A Mäkitie; Primož Strojan; June Corry; Avraham Eisbruch; Jonathan J Beitler; Sandra Nuyts; Robert Smee; Johannes A Langendijk; William M Mendenhall; Cesare Piazza; Alessandra Rinaldo; Alfio Ferlito
Journal:  Adv Ther       Date:  2020-11-13       Impact factor: 3.845

  2 in total

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