Literature DB >> 20097742

The Aspergillus fumigatus P-type Golgi apparatus Ca2+/Mn2+ ATPase PmrA is involved in cation homeostasis and cell wall integrity but is not essential for pathogenesis.

Nadthanan Pinchai1, Praveen Rao Juvvadi, Jarrod R Fortwendel, B Zachary Perfect, Luise E Rogg, Yohannes G Asfaw, William J Steinbach.   

Abstract

The Aspergillus fumigatus DeltapmrA (Golgi apparatus Ca(2+)/Mn(2+) P-type ATPase) strain has osmotically suppressible basal growth defects and cationic tolerance associated with increased expression of calcineurin pathway genes. Despite increased beta-glucan and chitin content, it is hypersensitive to cell wall inhibitors but remains virulent, suggesting a role for PmrA in cation homeostasis and cell wall integrity.

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Year:  2010        PMID： 20097742      PMCID： PMC2837981          DOI： 10.1128/EC.00378-09

Source DB:  PubMed          Journal:  Eukaryot Cell        ISSN： 1535-9786


  26 in total

1.  Cloning of the Aspergillus niger pmrA gene, a homologue of yeast PMR1, and characterization of a pmrA null mutant.

Authors:  J Yang; H A Kang; S M Ko; S K Chae; D D Ryu; J Y Kim
Journal:  FEMS Microbiol Lett       Date:  2001-05-15       Impact factor: 2.742

2.  Mutation in PMR1, a Ca(2+)-ATPase in Golgi, confers salt tolerance in Saccharomyces cerevisiae by inducing expression of PMR2, an Na(+)-ATPase in plasma membrane.

Authors:  S Y Park; S B Seo; S J Lee; J G Na; Y J Kim
Journal:  J Biol Chem       Date:  2001-05-31       Impact factor: 5.157

3.  Calcineurin-dependent growth control in Saccharomyces cerevisiae mutants lacking PMC1, a homolog of plasma membrane Ca2+ ATPases.

Authors:  K W Cunningham; G R Fink
Journal:  J Cell Biol       Date:  1994-02       Impact factor: 10.539

4.  Schizosaccharomyces pombe Pmr1p is essential for cell wall integrity and is required for polarized cell growth and cytokinesis.

Authors:  Juan Carlos G Cortés; Reiko Katoh-Fukui; Kanako Moto; Juan Carlos Ribas; Junpei Ishiguro
Journal:  Eukaryot Cell       Date:  2004-10

5.  The yeast Ca(2+)-ATPase homologue, PMR1, is required for normal Golgi function and localizes in a novel Golgi-like distribution.

Authors:  A Antebi; G R Fink
Journal:  Mol Biol Cell       Date:  1992-06       Impact factor: 4.138

6.  Zinc finger protein Prz1 regulates Ca2+ but not Cl- homeostasis in fission yeast. Identification of distinct branches of calcineurin signaling pathway in fission yeast.

Authors:  Sonoko Hirayama; Reiko Sugiura; Yabin Lu; Takuya Maeda; Kenji Kawagishi; Mistuhiro Yokoyama; Hideki Tohda; Yuko Giga-Hama; Hisato Shuntoh; Takayoshi Kuno
Journal:  J Biol Chem       Date:  2003-03-13       Impact factor: 5.157

7.  The protein phosphatase calcineurin is essential for NaCl tolerance of Saccharomyces cerevisiae.

Authors:  I Mendoza; F Rubio; A Rodriguez-Navarro; J M Pardo
Journal:  J Biol Chem       Date:  1994-03-25       Impact factor: 5.157

8.  The yeast secretory pathway is perturbed by mutations in PMR1, a member of a Ca2+ ATPase family.

Authors:  H K Rudolph; A Antebi; G R Fink; C M Buckley; T E Dorman; J LeVitre; L S Davidow; J I Mao; D T Moir
Journal:  Cell       Date:  1989-07-14       Impact factor: 41.582

Review 9.  Calcineurin signaling in Saccharomyces cerevisiae: how yeast go crazy in response to stress.

Authors:  Martha S Cyert
Journal:  Biochem Biophys Res Commun       Date:  2003-11-28       Impact factor: 3.575

10.  Mutations in PMR1 suppress oxidative damage in yeast cells lacking superoxide dismutase.

Authors:  P J Lapinskas; K W Cunningham; X F Liu; G R Fink; V C Culotta
Journal:  Mol Cell Biol       Date:  1995-03       Impact factor: 4.272
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  16 in total

1.  Role of Aspergillus fumigatus DvrA in host cell interactions and virulence.

Authors:  Daniele E Ejzykowicz; Norma V Solis; Fabrice N Gravelat; Josee Chabot; Xuexian Li; Donald C Sheppard; Scott G Filler
Journal:  Eukaryot Cell       Date:  2010-07-30

2.  Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.

Authors:  Praveen R Juvvadi; M Arthur Moseley; Christopher J Hughes; Erik J Soderblom; Sarah Lennon; Simon R Perkins; J Will Thompson; Scott J Geromanos; Jason Wildgoose; Keith Richardson; James I Langridge; Johannes P C Vissers; William J Steinbach
Journal:  J Proteome Res       Date:  2017-12-29       Impact factor: 4.466

3.  Calcineurin as a Multifunctional Regulator: Unraveling Novel Functions in Fungal Stress Responses, Hyphal Growth, Drug Resistance, and Pathogenesis.

Authors:  Praveen R Juvvadi; Frédéric Lamoth; William J Steinbach
Journal:  Fungal Biol Rev       Date:  2014-10       Impact factor: 4.706

Review 4.  Aspergillus fumigatus and Aspergillosis in 2019.

Authors:  Jean-Paul Latgé; Georgios Chamilos
Journal:  Clin Microbiol Rev       Date:  2019-11-13       Impact factor: 26.132

5.  The virulence of the opportunistic fungal pathogen Aspergillus fumigatus requires cooperation between the endoplasmic reticulum-associated degradation pathway (ERAD) and the unfolded protein response (UPR).

Authors:  Daryl L Richie; Xizhi Feng; Lukas Hartl; Vishukumar Aimanianda; Karthik Krishnan; Margaret V Powers-Fletcher; Douglas S Watson; Amit K Galande; Stephanie M White; Taryn Willett; Jean-Paul Latgé; Judith C Rhodes; David S Askew
Journal:  Virulence       Date:  2011-01-01       Impact factor: 5.882

6.  The sterol C-14 reductase Erg24 is responsible for ergosterol biosynthesis and ion homeostasis in Aspergillus fumigatus.

Authors:  Yeqi Li; Mengyao Dai; Yuanwei Zhang; Ling Lu
Journal:  Appl Microbiol Biotechnol       Date:  2021-01-21       Impact factor: 4.813

7.  The pmr gene, encoding a Ca2+-ATPase, is required for calcium and manganese homeostasis and normal development of hyphae and conidia in Neurospora crassa.

Authors:  Barry J Bowman; Stephen Abreu; Jessica K Johl; Emma Jean Bowman
Journal:  Eukaryot Cell       Date:  2012-09-14

8.  Functional characterization of an Aspergillus fumigatus calcium transporter (PmcA) that is essential for fungal infection.

Authors:  Taísa Magnani Dinamarco; Fernanda Zanolli Freitas; Ricardo S Almeida; Neil Andrew Brown; Thaila Fernanda dos Reis; Leandra Naira Zambelli Ramalho; Marcela Savoldi; Maria Helena S Goldman; Maria Célia Bertolini; Gustavo Henrique Goldman
Journal:  PLoS One       Date:  2012-05-23       Impact factor: 3.240

9.  The key target of neuroprotection after the onset of ischemic stroke: secretory pathway Ca(2+)-ATPase 1.

Authors:  Li-Hua Li; Xiang-Rong Tian; Zhi-Ping Hu
Journal:  Neural Regen Res       Date:  2015-08       Impact factor: 5.135

10.  The involvement of the Mid1/Cch1/Yvc1 calcium channels in Aspergillus fumigatus virulence.

Authors:  Patrícia Alves de Castro; Jéssica Chiaratto; Lizziane K Winkelströter; Vinícius Leite Pedro Bom; Leandra Naira Zambelli Ramalho; Maria Helena S Goldman; Neil Andrew Brown; Gustavo H Goldman
Journal:  PLoS One       Date:  2014-08-01       Impact factor: 3.240
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