| Literature DB >> 20096634 |
Vanesa Y Rawe1, Heydy Uriondo Boudri, Cristian Alvarez Sedó, Martina Carro, Sergio Papier, Florencia Nodar.
Abstract
Magnetic activated cell sorting (MACS) with annexin V microbeads recognizes externalized phosphatidylserine (PS) residues on the surface of apoptotic spermatozoa. The successful use of this novel technique applied to a highly apoptotic semen sample before performing intracytoplasmic sperm injection (ICSI) is reported here. The use of annexin V microbeads for selecting non-apoptotic spermatozoa seems to reduce the percentage of altered cells, improving the chance of pregnancy after ICSI. Copyright 2009 Reproductive Healthcare Ltd. Published by Elsevier Ltd. All rights reserved.Entities:
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Year: 2009 PMID: 20096634 DOI: 10.1016/j.rbmo.2009.12.004
Source DB: PubMed Journal: Reprod Biomed Online ISSN: 1472-6483 Impact factor: 3.828