Literature DB >> 20095963

Hydroquinone for skin lightening: safety profile, duration of use and when should we stop?

Tsz Wah Tse1.   

Abstract

Hydroquinone has been marketed in skin-lightening products for almost 50 years and remains as the most frequently used whitening constituent in the category. Issues and concerns have been raised regarding its potential dermatological and systemic side effects. These almost led to it being banned from the US market by the FDA in 2006. This article reviews its safety profile. The author also suggests on the duration of its use and advises on regular assessments by medical physicians.

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Year:  2010        PMID: 20095963     DOI: 10.3109/09546630903341945

Source DB:  PubMed          Journal:  J Dermatolog Treat        ISSN: 0954-6634            Impact factor:   3.359


  11 in total

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Authors:  Mariah L Scott; Mary F Adams; Joseph J Karchesy; Janet C McAllister
Journal:  J Med Entomol       Date:  2017-05-01       Impact factor: 2.278

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Journal:  Nanomaterials (Basel)       Date:  2022-06-05       Impact factor: 5.719

3.  Resveratrol-Enriched Rice Down-Regulates Melanin Synthesis in UVB-Induced Guinea Pigs Epidermal Skin Tissue.

Authors:  Taek Hwan Lee; Jae Ok Seo; Moon Ho Do; Eunhee Ji; So-Hyeon Baek; Sun Yeou Kim
Journal:  Biomol Ther (Seoul)       Date:  2014-09-30       Impact factor: 4.634

4.  Involvement of Transient Receptor Potential Cation Channel Member A1 activation in the irritation and pain response elicited by skin-lightening reagent hydroquinone.

Authors:  Yan Tai; Chuan Wang; Zhihua Wang; Yi Liang; Junying Du; Dongwei He; Xiaoyan Fan; Sven-Eric Jordt; Boyi Liu
Journal:  Sci Rep       Date:  2017-08-08       Impact factor: 4.379

5.  Antioxidants from the Brown Alga Dictyopteris undulata.

Authors:  Momochika Kumagai; Keisuke Nishikawa; Hiroshi Matsuura; Taiki Umezawa; Fuyuhiko Matsuda; Tatsufumi Okino
Journal:  Molecules       Date:  2018-05-18       Impact factor: 4.411

6.  Leathesia difformis Extract Inhibits α-MSH-Induced Melanogenesis in B16F10 Cells via Down-Regulation of CREB Signaling Pathway.

Authors:  Ga-Young Seo; Yuna Ha; Ah-Hyun Park; Oh Wook Kwon; Youn-Jung Kim
Journal:  Int J Mol Sci       Date:  2019-01-28       Impact factor: 5.923

7.  Effects of Skin Lightening Cream Agents - Hydroquinone and Kojic Acid, on the Skin of Adult Female Experimental Rats.

Authors:  Joshua Oladele Owolabi; Oluseyi Sunday Fabiyi; Lola Adeola Adelakin; Miriammillicent Chinenyenwa Ekwerike
Journal:  Clin Cosmet Investig Dermatol       Date:  2020-04-06

8.  Trends in Use of Prescription Skin Lightening Creams.

Authors:  Dana S Saade; Mayra B C Maymone; Henriette De La Garza; Eric A Secemsky; Kevin F Kennedy; Neelam A Vashi
Journal:  Int J Environ Res Public Health       Date:  2021-05-25       Impact factor: 3.390

9.  Cosmeceuticals for Hyperpigmentation: What is Available?

Authors:  Rashmi Sarkar; Pooja Arora; K Vijay Garg
Journal:  J Cutan Aesthet Surg       Date:  2013-01

Review 10.  Metabolic Basis and Clinical Evidence for Skin Lightening Effects of Thiol Compounds.

Authors:  Yong Chool Boo
Journal:  Antioxidants (Basel)       Date:  2022-03-04
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