Literature DB >> 20093940

Anterior segment transplantation with a novel biosynthetic graft.

Soosan Jacob1, Gaurav Prakash, Dhivya Ashok Kumar, Vidya Nair, Athiya Agarwal, Amar Agarwal.   

Abstract

PURPOSE: Staphylectomy with sclerokeratoplasty has been performed in cases with large anterior staphyloma. This report describes a technique using a new biosynthetic graft to simulate the anterior segment in the eye of a 4-month-old child with diffuse anterior staphyloma and cataractous lens with compromised zonules.
METHODS: The graft had a biologic part (corneoscleral button) and a synthetic part (aniridia intraocular lens). Two partial thickness flaps and sclerotomies were made in the graft through which the lens haptics were externalized. After staphylectomy and lensectomy of the host, the graft was sutured. After intrascleral tuck of the lens haptics before fibrin glue-assisted flap closure was then done.
RESULTS: On the first postoperative day, the child was following light with the operated eye, and closure of the lids and cosmesis were markedly improved. Between the first and fourth month follow-up, and with the normal eye occluded, the child was following light and reaching out for objects. The cornea was clear with no evidence of rejection or failure. At 5 months, a persistent epithelial defect developed, leading by 6 months into a nebulomacular opacity partially obscuring the pupil. At 6 months, the results of the technique are anatomically and cosmetically satisfactory; however, a longer follow-up term will establish the visual benefits.
CONCLUSIONS: This technique may provide a suitable cosmetic and anatomic alternative to conventional procedures like staphylectomy with sclerokeratoplasty. It also retains the potential for more effective visual rehabilitation as an intraocular lens has been implanted.

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Year:  2010        PMID: 20093940     DOI: 10.1097/ICL.0b013e3181cd1b14

Source DB:  PubMed          Journal:  Eye Contact Lens        ISSN: 1542-2321            Impact factor:   2.018


  4 in total

1.  Glued intraocular lens implantation for eyes with defective capsules: A retrospective analysis of anatomical and functional outcome.

Authors:  Dhivya A Kumar; Athiya Agarwal; Amar Agarwal; Gaurav Prakash; Soosan Jacob
Journal:  Saudi J Ophthalmol       Date:  2011-04-15

2.  Staged penetrating sclerokeratoplasty and penetrating keratoplasty for management of advanced acquired anterior staphyloma.

Authors:  Enrique de la Torre-Gonzalez; Carolina Ponce de León Ascencio
Journal:  J Ophthalmic Vis Res       Date:  2011-04

3.  Boston keratoprosthesis and Ahmed glaucoma valve for visual rehabilitation in congenital anterior staphyloma.

Authors:  Bhaskar Srinivasan; Nikhil Shreeram Choudhari; Aditya Neog; Supriya Latka; Geetha K Iyer
Journal:  Indian J Ophthalmol       Date:  2012 May-Jun       Impact factor: 1.848

4.  Histopathological examination of congenital corneal staphyloma and prognosis after penetrating keratoplasty.

Authors:  Yu Wan; Gege Xiao; Ting Yu; Pei Zhang; Jing Hong
Journal:  Medicine (Baltimore)       Date:  2020-10-02       Impact factor: 1.817

  4 in total

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