Literature DB >> 2009250

Key factors in the treatment of the elderly hypertensive.

J L Dall1.   

Abstract

Cardiovascular diseases are of fundamental importance in the cause of death and morbidity in the elderly as a group. If the successful management of blood pressure can effect a reduction in morbid events as well as death, as has been indicated by recent trials, the elderly have more to gain than any other group within the population by adequate treatment of blood pressure. The physiologic response to aging in the cardiovascular system has characteristics similar to a beta-adrenergic blocking effect. Some similar changes are seen in older hypertensives. Hypertension may represent premature aging in the cardiovascular system. Blood pressure can be reduced in elderly people, and it is now relevant to determine whether one particular method of reducing blood pressure has advantages over others. Education of the elderly as to the advantages of treatment is important, but education of professionals who prescribe is, perhaps, more important. A clear understanding of the gains to be made and the side effects of different groups of drugs is necessary to allow the doctor to prescribe confidently for the elderly patient.

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Mesh:

Year:  1991        PMID: 2009250     DOI: 10.1007/bf00114231

Source DB:  PubMed          Journal:  Cardiovasc Drugs Ther        ISSN: 0920-3206            Impact factor:   3.727


  10 in total

1.  Aging and cardiac function.

Authors:  D G Renlund; G Gerstenblith
Journal:  Int J Cardiol       Date:  1986-03       Impact factor: 4.164

2.  Essential hypertension in the elderly: haemodynamics, intravascular volume, plasma renin activity, and circulating catecholamine levels.

Authors:  F H Messerli; K Sundgaard-Riise; H O Ventura; F G Dunn; L B Glade; E D Frohlich
Journal:  Lancet       Date:  1983-10-29       Impact factor: 79.321

Review 3.  Diminished beta-adrenergic modulation of cardiovascular function in advanced age.

Authors:  E G Lakatta
Journal:  Cardiol Clin       Date:  1986-05       Impact factor: 2.213

4.  The effect of age on beta-adrenergic function in man: a review.

Authors:  R P Ebstein; J Stessman; R Eliakim; J Menczel
Journal:  Isr J Med Sci       Date:  1985-03

5.  Decreased beta-adrenergic responsiveness during senescence.

Authors:  P J Scarpace
Journal:  Fed Proc       Date:  1986-01

6.  Mortality and morbidity results from the European Working Party on High Blood Pressure in the Elderly trial.

Authors:  A Amery; W Birkenhäger; P Brixko; C Bulpitt; D Clement; M Deruyttere; A De Schaepdryver; C Dollery; R Fagard; F Forette
Journal:  Lancet       Date:  1985-06-15       Impact factor: 79.321

7.  Components of blood pressure and risk of atherothrombotic brain infarction: the Framingham study.

Authors:  W B Kannel; T R Dawber; P Sorlie; P A Wolf
Journal:  Stroke       Date:  1976 Jul-Aug       Impact factor: 7.914

8.  Five-year findings of the hypertension detection and follow-up program. I. Reduction in mortality of persons with high blood pressure, including mild hypertension. Hypertension Detection and Follow-up Program Cooperative Group.

Authors: 
Journal:  JAMA       Date:  1979-12-07       Impact factor: 56.272

9.  Exercise cardiac output is maintained with advancing age in healthy human subjects: cardiac dilatation and increased stroke volume compensate for a diminished heart rate.

Authors:  R J Rodeheffer; G Gerstenblith; L C Becker; J L Fleg; M L Weisfeldt; E G Lakatta
Journal:  Circulation       Date:  1984-02       Impact factor: 29.690

10.  The Australian therapeutic trial in mild hypertension. Report by the Management Committee.

Authors: 
Journal:  Lancet       Date:  1980-06-14       Impact factor: 202.731

  10 in total

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