Literature DB >> 20092326

Synthesis and biological evaluation of caffeic acid 3,4-dihydroxyphenethyl ester.

Zhizhen Zhang1, Binghua Xiao, Qi Chen, Xiao-Yuan Lian.   

Abstract

A high-yield synthesis of caffeic acid 3,4-dihydroxyphenethyl ester (1) has been achieved through Knoevenagel condensation of 3,4-dihydroxybenzaldehyde and 3,4-dihydroxyphenethyl monomalonate as the key step. Compound 1 was tested against a 56-cell-line cytotoxicity panel and for its free-radical-scavenging activity in the DPPH test.

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Year:  2010        PMID： 20092326     DOI： 10.1021/np900519d

Source DB:  PubMed          Journal:  J Nat Prod        ISSN： 0163-3864            Impact factor:   4.050


  8 in total

1.  Inhibitory effects of caffeic acid phenethyl ester derivatives on replication of hepatitis C virus.

Authors:  Hui Shen; Atsuya Yamashita; Masamichi Nakakoshi; Hiromasa Yokoe; Masashi Sudo; Hirotake Kasai; Tomohisa Tanaka; Yuusuke Fujimoto; Masanori Ikeda; Nobuyuki Kato; Naoya Sakamoto; Hiroko Shindo; Shinya Maekawa; Nobuyuki Enomoto; Masayoshi Tsubuki; Kohji Moriishi
Journal:  PLoS One       Date:  2013-12-17       Impact factor: 3.240

2.  Five New Phenolic Compounds with Antioxidant Activities from the Medicinal Insect Blaps rynchopetera.

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Journal:  Molecules       Date:  2017-08-04       Impact factor: 4.411

Review 3.  Caffeates and Caffeamides: Synthetic Methodologies and Their Antioxidant Properties.

Authors:  Merly de Armas-Ricard; Enrique Ruiz-Reyes; Oney Ramírez-Rodríguez
Journal:  Int J Med Chem       Date:  2019-11-11

4.  New Drimane Sesquiterpenes and Polyketides from Marine-Derived Fungus Penicillium sp. TW58-16 and Their Anti-Inflammatory and α-Glucosidase Inhibitory Effects.

Authors:  Xiaoshuang Gou; Danmei Tian; Jihua Wei; Yihan Ma; Yixue Zhang; Mei Chen; Wenjuan Ding; Bin Wu; Jinshan Tang
Journal:  Mar Drugs       Date:  2021-07-26       Impact factor: 5.118

5.  Synthesis, evaluation of anticancer activity and QSAR study of heterocyclic esters of caffeic Acid.

Authors:  Shima Hajmohamad Ebrahim Ketabforoosh; Mohsen Amini; Mohsen Vosooghi; Abbas Shafiee; Ebrahim Azizi; Farzad Kobarfard
Journal:  Iran J Pharm Res       Date:  2013       Impact factor: 1.696

6.  Synthesis and antiradical/antioxidant activities of caffeic acid phenethyl ester and its related propionic, acetic, and benzoic acid analogues.

Authors:  Luc M LeBlanc; Aurélie F Paré; Jacques Jean-François; Martin J G Hébert; Marc E Surette; Mohamed Touaibia
Journal:  Molecules       Date:  2012-12-10       Impact factor: 4.411

7.  Synthesis and Antioxidant Activity of Caffeic Acid Derivatives.

Authors:  Katarzyna Sidoryk; Anna Jaromin; Nina Filipczak; Piotr Cmoch; Marcin Cybulski
Journal:  Molecules       Date:  2018-08-30       Impact factor: 4.411

8.  Inducing apoptosis effect of caffeic acid 3,4-dihydroxy-phenethyl ester on the breast cancer cells.

Authors:  Jiaoyuan Jia; Mei Yang; Yu Chen; Hongyan Yuan; Jinghe Li; Xueling Cui; Zhonghui Liu
Journal:  Tumour Biol       Date:  2014-09-05
  8 in total

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