Literature DB >> 20092090

Getting it right: optimizing transfusion management during the procedure.

Darryl McMillan1, Kieran Potger, Joanne Southwell, Mark Ambrose, Terry Connolly, Margaret Louis.   

Abstract

There is little doubt that blood transfusions have saved many lives in cases of acute hypovolemia and anemia, but both the literature and practitioners still do not agree as to what the appropriate indicators for transfusion are in a cardiac surgical patient. Furthermore, there are those who claim that the benefit of blood transfusions has never been conclusively demonstrated, and evidence of transfusion related harm continues to accumulate. Cardiac surgical patients may be transfused not only because of bleeding but also due to hemodilution from preoperative and intraoperative intravenous fluids and pump primes in conjunction with a possible preoperative anemia. Getting transfusion right to improve our practice has to be approached multifactorially. The use of prophylactic dosing of blood products has been suggested to be ineffective in reducing blood loss. There are many factors that impact transfusion rates including determining the optimal hematocrit where it is highly unlikely that one figure will be applicable to all patients. The formulation of transfusion guidelines and algorithms that have been agreed upon by all practitioners involved in the care of cardiac surgical patients may have a positive effect-if everyone agrees to transfuse patients via the formulated guidelines or algorithms. Importantly, no one individual should be able make the decision on whether a patient requires a blood transfusion-it must at all times be a team decision, whether in the operating room or intensive care unit.

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Mesh:

Year:  2009        PMID: 20092090      PMCID: PMC4813542     

Source DB:  PubMed          Journal:  J Extra Corpor Technol        ISSN: 0022-1058


  45 in total

1.  Blood transfusion is associated with increased resource utilisation, morbidity and mortality in cardiac surgery.

Authors:  Bharathi H Scott; Frank C Seifert; Roger Grimson
Journal:  Ann Card Anaesth       Date:  2008 Jan-Jun

2.  Low hematocrit during cardiopulmonary bypass is associated with increased risk of perioperative stroke in cardiac surgery.

Authors:  Keyvan Karkouti; George Djaiani; Michael A Borger; William S Beattie; Ludwik Fedorko; Duminda Wijeysundera; Joan Ivanov; Jacek Karski
Journal:  Ann Thorac Surg       Date:  2005-10       Impact factor: 4.330

3.  Hemodilution during cardiopulmonary bypass is an independent risk factor for acute renal failure in adult cardiac surgery.

Authors:  K Karkouti; W S Beattie; D N Wijeysundera; V Rao; C Chan; K M Dattilo; G Djaiani; J Ivanov; J Karski; T E David
Journal:  J Thorac Cardiovasc Surg       Date:  2005-02       Impact factor: 5.209

Review 4.  The silent risks of blood transfusion.

Authors:  James Rawn
Journal:  Curr Opin Anaesthesiol       Date:  2008-10       Impact factor: 2.706

5.  Surgical reexploration after cardiac operations: why a worse outcome?

Authors:  Marco Ranucci; Giuseppe Bozzetti; Antonio Ditta; Mauro Cotza; Giovanni Carboni; Andrea Ballotta
Journal:  Ann Thorac Surg       Date:  2008-11       Impact factor: 4.330

Review 6.  Evidence-based platelet transfusion guidelines.

Authors:  Sherrill J Slichter
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2007

Review 7.  The evidence-based use of FFP and cryoprecipitate for abnormalities of coagulation tests and clinical coagulopathy.

Authors:  Simon J Stanworth
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2007

8.  Platelet transfusions during coronary artery bypass graft surgery are associated with serious adverse outcomes.

Authors:  Bruce D Spiess; David Royston; Jerrold H Levy; Jane Fitch; Wulf Dietrich; Simon Body; John Murkin; Andrea Nadel
Journal:  Transfusion       Date:  2004-08       Impact factor: 3.157

9.  The impact of an hematocrit of 20% during normothermic cardiopulmonary bypass for elective low risk coronary artery bypass graft surgery on oxygen delivery and clinical outcome--a randomized controlled study [ISRCTN35655335].

Authors:  Christian von Heymann; Michael Sander; Achim Foer; Anja Heinemann; Bruce Spiess; Jan Braun; Michael Krämer; Joachim Grosse; Pascal Dohmen; Simon Dushe; Jürgen Halle; Wolfgang F Konertz; Klaus-Dieter Wernecke; Claudia Spies
Journal:  Crit Care       Date:  2006       Impact factor: 9.097

10.  The impact of administration of tranexamic acid in reducing the use of red blood cells and other blood products in cardiac surgery.

Authors:  Alain Vuylsteke; Palanikumar Saravanan; Caroline Gerrard; Fay Cafferty
Journal:  BMC Anesthesiol       Date:  2006-08-30       Impact factor: 2.217

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  1 in total

1.  Is cold blood cardioplegia absolutely superior to cold crystalloid cardioplegia in aortic valve surgery?

Authors:  Daniel A Lerman; Matilde Otero-Losada; Kiddy Ume; Pablo A Salgado; Sai Prasad; Kelvin Lim; Bruno Péault; Nasri Alotti
Journal:  J Cardiovasc Surg (Torino)       Date:  2017-05-26       Impact factor: 1.888

  1 in total

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