| Literature DB >> 2009100 |
A Pompella1, A Romani, A Benedetti, M Comporti.
Abstract
The data reported suggest that--following initiation of lipid peroxidation--membrane protein thiols can be attacked by lipid-derived radicals and/or reactive, lipid-soluble aldehydes like 4-hydroxynonenal and other hydroxyalkenals originated within the lipid core of cell membranes, resulting in a membrane protein thiol loss which is in turn associated with the development of hepatocellular injury.Entities:
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Year: 1991 PMID： 2009100 DOI： 10.1016/0006-2952(91)90666-s
Source DB: PubMed Journal: Biochem Pharmacol ISSN： 0006-2952 Impact factor: 5.858