Literature DB >> 20088778

Anesthesia and postoperative cognitive dysfunction (POCD).

Bettina Jungwirth1, Walter Zieglgänsberger, Eberhard Kochs, Gerhard Rammes.   

Abstract

POCD describes a decline in cognitive function after surgery with a predominance in the elderly patient. Although there is general agreement that POCD is likely to be multifactorial, whether its occurrence is a result of the effects of surgery or general anesthesia remains unclear. This review provides a synopsis of the available clinical and preclinical data and summarizes recent research relevant to the occurrence of POCD and possible pharmacologic algorithms for its prevention and treatment.

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Mesh：

Year:  2009        PMID： 20088778     DOI： 10.2174/138955709791012229

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  20 in total

1.  Anesthesia and surgery induce delirium-like behavior in susceptible mice: the role of oxidative stress.

Authors:  Jie Zhang; Jie Gao; Guojun Guo; Shan Li; Gaofeng Zhan; Zhongcong Xie; Chun Yang; Ailin Luo
Journal:  Am J Transl Res       Date:  2018-08-15       Impact factor: 4.060

2.  Isoflurane anesthesia aggravates cognitive impairment in streptozotocin-induced diabetic rats.

Authors:  Chun Yang; Bin Zhu; Jie Ding; Zhi-Gang Wang
Journal:  Int J Clin Exp Med       Date:  2014-04-15

3.  Ampelopsin alleviates sevoflurane-induced cognitive dysfunction by mediating NF-κB pathway in aged rats.

Authors:  Chenglong Liu; Xiaojuan Zha; Haihua Liu; Fang Wei; Fei Zhang
Journal:  Genes Genomics       Date:  2020-01-04       Impact factor: 1.839

4.  Effects of Single Low Dose of Dexamethasone before Noncardiac and Nonneurologic Surgery and General Anesthesia on Postoperative Cognitive Dysfunction-A Phase III Double Blind, Randomized Clinical Trial.

Authors:  Livia Stocco Sanches Valentin; Valeria Fontenelle Angelim Pereira; Ricardo S Pietrobon; Andre P Schmidt; Jean P Oses; Luis V Portela; Diogo O Souza; João Ricardo Nickenig Vissoci; Vinicius Fernando da Luz; Leticia Maria de Araujo de Souza Trintoni; Karen C Nielsen; Maria José Carvalho Carmona
Journal:  PLoS One       Date:  2016-05-06       Impact factor: 3.240

5.  Dilations of anastomotic strictures over time after repair of esophageal atresia.

Authors:  Pernilla Stenström; Magnus Anderberg; Anna Börjesson; Einar Arnbjörnsson
Journal:  Pediatr Surg Int       Date:  2016-11-15       Impact factor: 1.827

6.  Association Between ABO Blood Type and Postoperative Cognitive Dysfunction in Elderly Patients Undergoing Unilateral Total Hip Arthroplasty Surgery in China.

Authors:  Jie Li; Jun Zhou; Yunqiang Wan; Li Liu; Cehua Ou
Journal:  Med Sci Monit       Date:  2017-05-28

7.  Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, attenuates postoperative cognitive dysfunction in aging mice.

Authors:  Min Jia; Wen-Xue Liu; He-Liang Sun; Yan-Qing Chang; Jiao-Jiao Yang; Mu-Huo Ji; Jian-Jun Yang; Chen-Zhuo Feng
Journal:  Front Mol Neurosci       Date:  2015-09-23       Impact factor: 5.639

8.  Repeated Isoflurane Exposures Impair Long-Term Potentiation and Increase Basal GABAergic Activity in the Basolateral Amygdala.

Authors:  Robert P Long Ii; Vassiliki Aroniadou-Anderjaska; Eric M Prager; Volodymyr I Pidoplichko; Taiza H Figueiredo; Maria F M Braga
Journal:  Neural Plast       Date:  2016-05-23       Impact factor: 3.599

9.  Ratio of β-amyloid protein (Aβ) and Tau predicts the postoperative cognitive dysfunction on patients undergoing total hip/knee replacement surgery.

Authors:  Zhipeng Wu; Mei Zhang; Zhenhong Zhang; Wei Dong; Qingben Wang; Juan Ren
Journal:  Exp Ther Med       Date:  2017-11-10       Impact factor: 2.447

10.  The Effect of Dexmedetomidine and Esmolol on Early Postoperative Cognitive Dysfunction After Middle Ear Surgery Under Hypotensive Technique: A Comparative, Randomized, Double-blind Study.

Authors:  Mahmoud Hussein Bahr; Doaa Abu Elkassim Rashwan; Samaa A Kasem
Journal:  Anesth Pain Med       Date:  2020-12-02
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