| Literature DB >> 20088742 |
Neel R Sodha1, Louis M Chu, Munir Boodhwani, Frank W Sellke.
Abstract
IMPORTANCE OF THE FIELD: Coronary artery disease remains the leading cause of mortality in the industrialized world. Despite advances in surgical and catheter-based interventions, a select number of patients remain with no options for invasive therapy. The goal of this review is to discuss the current status of pharmacotherapeutic interventions to treat end-stage coronary artery disease. AREAS COVERED IN THIS REVIEW: Literature review on the topic of therapeutic angiogenesis from 1980 to 2009. WHAT THE READER WILL GAIN: Insight into current therapeutic strategies employed to manage end-stage coronary artery disease. TAKE HOME MESSAGE: A promising approach focuses on augmenting the endogenous angiogenic response to chronic myocardial ischemia via the use of growth factors.Entities:
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Year: 2010 PMID: 20088742 PMCID: PMC2811321 DOI: 10.1517/14656560903439737
Source DB: PubMed Journal: Expert Opin Pharmacother ISSN: 1465-6566 Impact factor: 3.889