Literature DB >> 20088731

Should routine screening by mammography be replaced by a more selective service of risk assessment/risk management?

Michael Baum1.   

Abstract

The NHS screening program was launched 20 years ago and, until recently, has been accepted in an uncritical way. However, emerging data have suggested that the reduction in breast cancer mortality owing to screening is much less than it has been credited for. Furthermore, the harms from false-positive results and the overdiagnosis of indolent disease, which includes the detection of a cancer that is not destined to present clinically in that patient's lifetime, are now perceived as much greater than ever anticipated. This article suggests that it is complacent to continue with the program unchecked, a program that has so far denied women an informed choice. It is also suggested that a more efficient use of scarce resources that may reduce all-cause mortality might be to shift from a 'one size fits all' approach, to a risk assessment/risk management scheme.

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Year:  2010        PMID: 20088731     DOI: 10.2217/whe.09.70

Source DB:  PubMed          Journal:  Womens Health (Lond)        ISSN: 1745-5057


  3 in total

1.  Most breast cancer screening trials have a flawed design.

Authors:  Nishant Gurnani; Anurag Srivastava
Journal:  Indian J Surg       Date:  2011-10-25       Impact factor: 0.656

2.  Testing breast cancer serum biomarkers for early detection and prognosis in pre-diagnosis samples.

Authors:  Anna Kazarian; Oleg Blyuss; Gergana Metodieva; Aleksandra Gentry-Maharaj; Andy Ryan; Elena M Kiseleva; Olga M Prytomanova; Ian J Jacobs; Martin Widschwendter; Usha Menon; John F Timms
Journal:  Br J Cancer       Date:  2017-01-12       Impact factor: 7.640

Review 3.  The current status of risk-stratified breast screening.

Authors:  Ash Kieran Clift; David Dodwell; Simon Lord; Stavros Petrou; Sir Michael Brady; Gary S Collins; Julia Hippisley-Cox
Journal:  Br J Cancer       Date:  2021-10-26       Impact factor: 9.075

  3 in total

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