Literature DB >> 20087792

Methadone toxicity in infants: a report of two fatalities.

V Mistry1, A J Jeffery, W Madira, C J H Padfield, G N Rutty.   

Abstract

Fatalities in infants resulting from methadone toxicity are rare within the United Kingdom. We report two cases of fatality attributed to methadone toxicity in infants aged 3(1/2) and 15 months of age, respectively. One of the two cases was also associated with diazepam ingestion. We discuss the difficulties with the interpretation of paediatric forensic toxicology and review the current literature related to methadone and diazepam toxicity in infants and older children.

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Year:  2010        PMID: 20087792     DOI: 10.1007/s12024-009-9138-0

Source DB:  PubMed          Journal:  Forensic Sci Med Pathol        ISSN: 1547-769X            Impact factor:   2.007


  20 in total

1.  Estimating antemortem drug concentrations from postmortem blood samples: the influence of postmortem redistribution.

Authors:  D S Cook; R A Braithwaite; K A Hale
Journal:  J Clin Pathol       Date:  2000-04       Impact factor: 3.411

Review 2.  Value of hair analysis in postmortem toxicology.

Authors:  Pascal Kintz
Journal:  Forensic Sci Int       Date:  2004-06-10       Impact factor: 2.395

Review 3.  Are one or two dangerous? Opioid exposure in toddlers.

Authors:  Deepak K Sachdeva; John M Stadnyk
Journal:  J Emerg Med       Date:  2005-07       Impact factor: 1.484

4.  Methadone deaths: a toxicological analysis.

Authors:  C M Milroy; A R Forrest
Journal:  J Clin Pathol       Date:  2000-04       Impact factor: 3.411

5.  Fatal methadone poisoning in children: report of four cases.

Authors:  D J DiMaio; T DiMaio
Journal:  J Forensic Sci       Date:  1973-04       Impact factor: 1.832

6.  Enteral absorption and bioavailability in children in relation to age.

Authors:  G Heimann
Journal:  Eur J Clin Pharmacol       Date:  1980-07       Impact factor: 2.953

7.  Detection of stimulant drugs of abuse in maternal and neonatal hair.

Authors:  Facundo Garcia-Bournissen; Ben Rokach; Tatyana Karaskov; Joey Gareri; Gideon Koren
Journal:  Forensic Sci Med Pathol       Date:  2007-09-05       Impact factor: 2.007

8.  Toxicologic analysis in cases of possible sudden infant death syndrome: a worthwhile exercise?

Authors:  Neil E I Langlois; Peter S Ellis; Dianne Little; Bogdan Hulewicz
Journal:  Am J Forensic Med Pathol       Date:  2002-06       Impact factor: 0.921

9.  Methadone as a chemical weapon: two fatal cases involving babies.

Authors:  Pascal Kintz; Marion Villain; Véronique Dumestre-Toulet; Bernard Capolaghi; Vincent Cirimele
Journal:  Ther Drug Monit       Date:  2005-12       Impact factor: 3.681

10.  Fatal methadone intoxication in an infant.

Authors:  Fiona J Couper; Kiran Chopra; Marie Lydie Y Pierre-Louis
Journal:  Forensic Sci Int       Date:  2005-10-04       Impact factor: 2.395

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  1 in total

1.  The Role of Risk or Contributory Death Factors in Methadone-Related Fatalities: A Review and Pooled Analysis.

Authors:  Arianna Giorgetti; Jennifer Pascali; Massimo Montisci; Irene Amico; Barbara Bonvicini; Paolo Fais; Alessia Viero; Raffaele Giorgetti; Giovanni Cecchetto; Guido Viel
Journal:  Metabolites       Date:  2021-03-22
  1 in total

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