Literature DB >> 20087680

Overview of a HLA-Ig based "Lego-like system" for T cell monitoring, modulation and expansion.

Mathias Oelke1, Jonathan P Schneck.   

Abstract

Recent advances in molecular medicine have shown that soluble MHC-multimers can be valuable tools for both analysis and modulation of antigen-specific immune responses in vitro and in vivo. In this review, we describe the use of dimeric human and mouse major histocompatibility complexes, MHC-Ig, as part of an artificial Antigen-Presenting Cell (aAPC). MHC-Ig-based aAPC and its derivatives represent an exciting new platform technology for measuring and manipulating immune responses in vitro as well as in vivo. This new technology has the potential to help overcome many of the obstacles associated with limitations in current antigen-specific approaches of immunotherapy for the treatment of cancer, infectious diseases and autoimmunity.

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Year:  2010        PMID： 20087680      PMCID： PMC2891436          DOI： 10.1007/s12026-009-8156-z

Source DB:  PubMed          Journal:  Immunol Res        ISSN： 0257-277X            Impact factor:   2.829


  46 in total

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Review 2.  Going both ways: immune regulation via CD1d-dependent NKT cells.

Authors:  Dale I Godfrey; Mitchell Kronenberg
Journal:  J Clin Invest       Date:  2004-11       Impact factor: 14.808

Review 3.  Technological advances in adoptive immunotherapy.

Authors:  Mathias Oelke; Christine Krueger; Jonathan P Schneck
Journal:  Drugs Today (Barc)       Date:  2005-01       Impact factor: 2.245

4.  Initiation of signal transduction through the T cell receptor requires the multivalent engagement of peptide/MHC ligands [corrected].

Authors:  J J Boniface; J D Rabinowitz; C Wülfing; J Hampl; Z Reich; J D Altman; R M Kantor; C Beeson; H M McConnell; M M Davis
Journal:  Immunity       Date:  1998-10       Impact factor: 31.745

5.  The fate of low affinity tumor-specific CD8+ T cells in tumor-bearing mice.

Authors:  Michael A Lyman; C Thomas Nugent; Kristi L Marquardt; Judith A Biggs; Eric G Pamer; Linda A Sherman
Journal:  J Immunol       Date:  2005-03-01       Impact factor: 5.422

Review 6.  Part I: Vaccines for solid tumours.

Authors:  Simone Mocellin; Susanna Mandruzzato; Vincenzo Bronte; Mario Lise; Donato Nitti
Journal:  Lancet Oncol       Date:  2004-11       Impact factor: 41.316

7.  Early quantitative and functional deficiency of NK1+-like thymocytes in the NOD mouse.

Authors:  J M Gombert; A Herbelin; E Tancrède-Bohin; M Dy; C Carnaud; J F Bach
Journal:  Eur J Immunol       Date:  1996-12       Impact factor: 5.532

Review 8.  Mechanisms and functional significance of tumour-induced dendritic-cell defects.

Authors:  Dmitry Gabrilovich
Journal:  Nat Rev Immunol       Date:  2004-12       Impact factor: 53.106

9.  Phenotypic analysis of antigen-specific T lymphocytes.

Authors:  J D Altman; P A Moss; P J Goulder; D H Barouch; M G McHeyzer-Williams; J I Bell; A J McMichael; M M Davis
Journal:  Science       Date:  1996-10-04       Impact factor: 47.728

10.  Direct visualization of antigen-specific T cells: HTLV-1 Tax11-19- specific CD8(+) T cells are activated in peripheral blood and accumulate in cerebrospinal fluid from HAM/TSP patients.

Authors:  T F Greten; J E Slansky; R Kubota; S S Soldan; E M Jaffee; T P Leist; D M Pardoll; S Jacobson; J P Schneck
Journal:  Proc Natl Acad Sci U S A       Date:  1998-06-23       Impact factor: 11.205
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  16 in total

Review 1.  Surface engineering for lymphocyte programming.

Authors:  Elana Ben-Akiva; Randall A Meyer; David R Wilson; Jordan J Green
Journal:  Adv Drug Deliv Rev       Date:  2017-05-10       Impact factor: 15.470

2.  Modulation of MHC binding by lateral association of TCR and coreceptor.

Authors:  Karlo Perica; Joan Glick Bieler; Michael Edidin; Jonathan Schneck
Journal:  Biophys J       Date:  2012-11-07       Impact factor: 4.033

3.  Antigen-specific activation and cytokine-facilitated expansion of naive, human CD8+ T cells.

Authors:  Matthias Wölfl; Philip D Greenberg
Journal:  Nat Protoc       Date:  2014-03-27       Impact factor: 13.491

4.  CD47 Enhances In Vivo Functionality of Artificial Antigen-Presenting Cells.

Authors:  Heiko Bruns; Catherine Bessell; Juan Carlos Varela; Carl Haupt; Jerry Fang; Shirin Pasemann; Andreas Mackensen; Mathias Oelke; Jonathan P Schneck; Christian Schütz
Journal:  Clin Cancer Res       Date:  2015-01-15       Impact factor: 12.531

Review 5.  Artificial antigen-presenting cells for use in adoptive immunotherapy.

Authors:  Cameron J Turtle; Stanley R Riddell
Journal:  Cancer J       Date:  2010 Jul-Aug       Impact factor: 3.360

Review 6.  Soluble MHC class I complexes for targeted immunotherapy.

Authors:  Anna Schappert; Jonathan P Schneck; Lauren Suarez; Mathias Oelke; Christian Schütz
Journal:  Life Sci       Date:  2018-08-10       Impact factor: 5.037

Review 7.  Biomaterials to enhance antigen-specific T cell expansion for cancer immunotherapy.

Authors:  Ariel Isser; Natalie K Livingston; Jonathan P Schneck
Journal:  Biomaterials       Date:  2020-12-05       Impact factor: 15.304

8.  Biomimetic biodegradable artificial antigen presenting cells synergize with PD-1 blockade to treat melanoma.

Authors:  A K Kosmides; R A Meyer; J W Hickey; K Aje; K N Cheung; J J Green; J P Schneck
Journal:  Biomaterials       Date:  2016-12-02       Impact factor: 12.479

9.  Nanoscale artificial antigen presenting cells for T cell immunotherapy.

Authors:  Karlo Perica; Andrés De León Medero; Malarvizhi Durai; Yen Ling Chiu; Joan Glick Bieler; Leah Sibener; Michaela Niemöller; Mario Assenmacher; Anne Richter; Michael Edidin; Mathias Oelke; Jonathan Schneck
Journal:  Nanomedicine       Date:  2013-07-24       Impact factor: 5.307

Review 10.  Linking form to function: Biophysical aspects of artificial antigen presenting cell design.

Authors:  Karlo Perica; Alyssa K Kosmides; Jonathan P Schneck
Journal:  Biochim Biophys Acta       Date:  2014-09-06
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