Literature DB >> 20087548

Surgery for the palliation of intestinal obstruction in advanced abdominal malignancy.

T H Wong1, Y M Tan.   

Abstract

INTRODUCTION: Intestinal obstruction commonly occurs in advanced abdominal and pelvic malignancy. Management of these patients is difficult, as it is uncertain which patients benefit from palliative surgery and which benefit from medical management.
METHODS: Clinical records for patients who underwent surgery for palliation of bowel obstruction were reviewed retrospectively. All had metastatic malignant disease and were seen by the general surgical department for intestinal obstruction. The following factors were examined: preoperative albumin, APACHE II score, age, site of metastases, presence of ascites, operative findings and type of operative procedure performed, length of postoperative stay and mortality.
RESULTS: 27 palliative operations for intestinal obstruction for metastatic malignancy were performed during this period. This included two patients who were re-operated on for recurrence of intestinal obstruction after recovering from the first operation. All patients had radiological evidence of intestinal obstruction preoperatively. All patients who survived were discharged from hospital without requiring parenteral nutrition or hydration, and were able to tolerate oral medication and feeds. In this small series, site of metastases, presence of ascites, APACHE II score and gender were not predictive of mortality. An albumin level of 21 g/L or less was predictive of mortality. Almost 50 percent of these patients would require a stoma. Our series had a 30-day mortality rate of 20 percent.
CONCLUSION: Surgery does have a role in palliation of symptoms of intestinal obstruction in carefully selected patients with advanced abdominal and pelvic malignancy. Patients should be counselled on the likelihood of a stoma and the 30-day mortality risk.

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Year:  2009        PMID: 20087548

Source DB:  PubMed          Journal:  Singapore Med J        ISSN: 0037-5675            Impact factor:   1.858


  4 in total

Review 1.  Surgery for the resolution of symptoms in malignant bowel obstruction in advanced gynaecological and gastrointestinal cancer.

Authors:  Sarah E Cousins; Emma Tempest; David J Feuer
Journal:  Cochrane Database Syst Rev       Date:  2016-01-04

2.  A scoring system for the prognosis and treatment of malignant bowel obstruction.

Authors:  Jon C Henry; Severin Pouly; Rachael Sullivan; Suhail Sharif; Dori Klemanski; Sherif Abdel-Misih; Nicole Arradaza; David Jarjoura; Carl Schmidt; Mark Bloomston
Journal:  Surgery       Date:  2012-08-26       Impact factor: 3.982

3.  Malignant bowel obstruction: A retrospective clinical analysis.

Authors:  Jia-Hong Chen; Tzu-Chuan Huang; Ping-Ying Chang; Ming-Shen Dai; Ching-Liang Ho; Yeu-Chin Chen; Tsu-Yi Chao; Woei-Yau Kao
Journal:  Mol Clin Oncol       Date:  2013-11-19

4.  Intestinal metastasis from primary epidermoid anal carcinoma in a 34 year old male presented with acute bowel obstruction.

Authors:  M Abdulmajed; A Ghalib; M Mohamed; P Marsh
Journal:  J Surg Case Rep       Date:  2012-02-01
  4 in total

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