| Literature DB >> 20085703 |
Abstract
The microtubule network is crucial for the developing nervous system, and mutations in tubulin-encoding genes disrupt neuronal migration. Tischfield et al. (2010) now report that mutations in the tubulin-encoding gene TUBB3 have a striking impact on microtubule dynamics in neurons, resulting in a diverse set of disease symptoms.Entities:
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Year: 2010 PMID: 20085703 DOI: 10.1016/j.cell.2009.12.038
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582