Literature DB >> 20085702

Chewing the fat on tumor cell metabolism.

Jessica L Yecies1, Brendan D Manning.   

Abstract

Tumor cells undergo a metabolic shift toward specific bioenergetic (glycolysis) and anabolic (protein and lipid synthesis) processes that promote rapid growth. Nomura et al. (2010) now demonstrate that an increase in monoacylglycerol lipase (MAGL) drives tumorigenesis through the lipolytic release and remodeling of free fatty acids.

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Year:  2010        PMID： 20085702     DOI： 10.1016/j.cell.2009.12.037

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  13 in total

1.  Fighting against cancer by integrative medicine.

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Journal:  Chin J Integr Med       Date:  2012-05-02       Impact factor: 1.978

2.  Ets-1 regulates energy metabolism in cancer cells.

Authors:  Meghan L Verschoor; Leigh A Wilson; Chris P Verschoor; Gurmit Singh
Journal:  PLoS One       Date:  2010-10-22       Impact factor: 3.240

3.  Dysregulated mTORC1 renders cells critically dependent on desaturated lipids for survival under tumor-like stress.

Authors:  Regina M Young; Daniel Ackerman; Zachary L Quinn; Anthony Mancuso; Michaela Gruber; Liping Liu; Dionysios N Giannoukos; Ekaterina Bobrovnikova-Marjon; J Alan Diehl; Brian Keith; M Celeste Simon
Journal:  Genes Dev       Date:  2013-05-15       Impact factor: 11.361

4.  Inhibition of fatty acid metabolism reduces human myeloma cells proliferation.

Authors:  José Manuel Tirado-Vélez; Insaf Joumady; Ana Sáez-Benito; Irene Cózar-Castellano; Germán Perdomo
Journal:  PLoS One       Date:  2012-09-28       Impact factor: 3.240

5.  SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker.

Authors:  Vamsi K Kolukula; Geetaram Sahu; Anton Wellstein; Olga C Rodriguez; Anju Preet; Vito Iacobazzi; Gabriella D'Orazi; Chris Albanese; Ferdinando Palmieri; Maria Laura Avantaggiati
Journal:  Oncotarget       Date:  2014-03-15

Review 6.  Teaching the basics of cancer metabolism: Developing antitumor strategies by exploiting the differences between normal and cancer cell metabolism.

Authors:  Balaraman Kalyanaraman
Journal:  Redox Biol       Date:  2017-04-13       Impact factor: 11.799

7.  Bone marrow adipocytes promote the Warburg phenotype in metastatic prostate tumors via HIF-1α activation.

Authors:  Jonathan D Diedrich; Erandi Rajagurubandara; Mackenzie K Herroon; Gargi Mahapatra; Maik Hüttemann; Izabela Podgorski
Journal:  Oncotarget       Date:  2016-10-04

Review 8.  A novel approach to the discovery of anti-tumor pharmaceuticals: searching for activators of liponecrosis.

Authors:  Anthony Arlia-Ciommo; Veronika Svistkova; Sadaf Mohtashami; Vladimir I Titorenko
Journal:  Oncotarget       Date:  2016-02-02

9.  Detection and Discrimination of Non-Melanoma Skin Cancer by Multimodal Imaging.

Authors:  Sandro Heuke; Nadine Vogler; Tobias Meyer; Denis Akimov; Franziska Kluschke; Hans-Joachim Röwert-Huber; Jürgen Lademann; Benjamin Dietzek; Jürgen Popp
Journal:  Healthcare (Basel)       Date:  2013-10-17

10.  ARS2/MAGL signaling in glioblastoma stem cells promotes self-renewal and M2-like polarization of tumor-associated macrophages.

Authors:  Jinlong Yin; Sung Soo Kim; Eunji Choi; Young Taek Oh; Weiwei Lin; Tae-Hoon Kim; Jason K Sa; Jun Hee Hong; Se Hwan Park; Hyung Joon Kwon; Xiong Jin; Yeonhee You; Ji Hye Kim; Hyunggee Kim; Jaekyoung Son; Jeongwu Lee; Do-Hyun Nam; Kui Son Choi; Bingyang Shi; Ho-Shin Gwak; Heon Yoo; Antonio Iavarone; Jong Heon Kim; Jong Bae Park
Journal:  Nat Commun       Date:  2020-06-12       Impact factor: 14.919
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