AIMS: To determine risk factors for recurrence of desmoid-type fibromatosis (aggressive fibromatosis). METHODS: Forty-six cases of desmoid-type fibromatosis in Taiwanese patients were analysed for an association between tumour recurrence and clinical features, pathology, and the presence of p53 protein and beta-catenin on immunohistochemical staining. RESULTS: Six (13%) of 46 patients developed recurrence after surgical resection. The only factor significantly associated with tumour recurrence was positive surgical margin (p = 0.035). CONCLUSIONS: A positive surgical margin is a risk factor for recurrence of desmoid-type fibromatosis.
AIMS: To determine risk factors for recurrence of desmoid-type fibromatosis (aggressive fibromatosis). METHODS: Forty-six cases of desmoid-type fibromatosis in Taiwanese patients were analysed for an association between tumour recurrence and clinical features, pathology, and the presence of p53 protein and beta-catenin on immunohistochemical staining. RESULTS: Six (13%) of 46 patients developed recurrence after surgical resection. The only factor significantly associated with tumour recurrence was positive surgical margin (p = 0.035). CONCLUSIONS: A positive surgical margin is a risk factor for recurrence of desmoid-type fibromatosis.
Authors: Firouzeh Kamali; Wei-Lien Wang; B A Guadagnolo; Patricia S Fox; Valerae O Lewis; Alexander J Lazar; Anthony P Conley; Vinod Ravi; Mohammad Toliyat; Harshad S Ladha; Brian P Hobbs; Behrang Amini Journal: Br J Radiol Date: 2015-11-18 Impact factor: 3.039