Therese F Mar1, Jane Q Koenig. 1. Department of Environmental and Occupational Sciences, University of Washington, Seattle, Washington 98195, USA.
Abstract
BACKGROUND: Air pollution is known to affect asthma symptoms in controlled and epidemiologic studies. OBJECTIVE: To determine whether ozone exposure in Seattle is associated with increased use of hospital emergency departments. METHODS: Hospital data on daily asthma cases for all ages were obtained for 1998 through 2002. Ozone and fine particulate matter (< or = 2.5 microm in diameter) (PM2.5) data were obtained from local air agencies. Poisson regression models were used to assess the association between asthma visits to emergency departments and air pollutants. Maximum daily 1- and 8-hour average ozone concentrations and the daily PM2.5 concentration were used. RESULTS: We observed associations between both ozone metrics and emergency department visits in children. For the maximum daily 1- and 8-hour average ozone concentrations, the relative risks (RRs) were 1.08 (95% confidence interval [CI], 1.00-1.18) and 1.11 (95% CI, 1.02-1.21), respectively, at 3 days' lag. Weaker but significant associations were also observed for adults. For the maximum daily 1-hour average ozone concentration, the RR was 1.06 (95% CI, 1.01-1.11) at 4 days' lag, and for the maximum daily 8-hour average ozone concentration, the RR was 1.06 (95% CI, 1.01-1.12) at 2 days' lag and 1.08 (95% CI, 1.02-1.14) at 4 days' lag. CONCLUSION: Ozone exposure exacerbates asthma in people in the Seattle area, especially in children.
BACKGROUND: Air pollution is known to affect asthma symptoms in controlled and epidemiologic studies. OBJECTIVE: To determine whether ozone exposure in Seattle is associated with increased use of hospital emergency departments. METHODS: Hospital data on daily asthma cases for all ages were obtained for 1998 through 2002. Ozone and fine particulate matter (< or = 2.5 microm in diameter) (PM2.5) data were obtained from local air agencies. Poisson regression models were used to assess the association between asthma visits to emergency departments and air pollutants. Maximum daily 1- and 8-hour average ozone concentrations and the daily PM2.5 concentration were used. RESULTS: We observed associations between both ozone metrics and emergency department visits in children. For the maximum daily 1- and 8-hour average ozone concentrations, the relative risks (RRs) were 1.08 (95% confidence interval [CI], 1.00-1.18) and 1.11 (95% CI, 1.02-1.21), respectively, at 3 days' lag. Weaker but significant associations were also observed for adults. For the maximum daily 1-hour average ozone concentration, the RR was 1.06 (95% CI, 1.01-1.11) at 4 days' lag, and for the maximum daily 8-hour average ozone concentration, the RR was 1.06 (95% CI, 1.01-1.12) at 2 days' lag and 1.08 (95% CI, 1.02-1.14) at 4 days' lag. CONCLUSION: Ozone exposure exacerbates asthma in people in the Seattle area, especially in children.
Authors: Kelsa Gabehart; Kelly A Correll; Jing Yang; Maureen L Collins; Joan E Loader; Sonia Leach; Carl W White; Azzeddine Dakhama Journal: Toxicol Sci Date: 2013-12-12 Impact factor: 4.849
Authors: Nicholas Nassikas; Keith Spangler; Neal Fann; Christopher G Nolte; Patrick Dolwick; Tanya L Spero; Perry Sheffield; Gregory A Wellenius Journal: Environ Res Date: 2020-01-31 Impact factor: 6.498
Authors: Sheryl Magzamen; Brianna F Moore; Michael G Yost; Richard A Fenske; Catherine J Karr Journal: J Occup Environ Med Date: 2017-07 Impact factor: 2.162
Authors: Lisa C Vinikoor-Imler; Elizabeth O Owens; Jennifer L Nichols; Mary Ross; James S Brown; Jason D Sacks Journal: Environ Health Perspect Date: 2014-06-13 Impact factor: 9.031
Authors: Brian J Malig; Dharshani L Pearson; Yun Brenda Chang; Rachel Broadwin; Rupa Basu; Rochelle S Green; Bart Ostro Journal: Environ Health Perspect Date: 2015-12-08 Impact factor: 9.031