Literature DB >> 2008415

Alcohol consumption does not affect fathers but does affect their offspring in the forced swimming test.

E L Abel1.   

Abstract

Male rats that had consumed alcohol for seven months did not differ significantly from controls in their immobility response in the forced swimming test. In contrast to this observation, the offspring of these males exhibited a significant dose-related decrease in immobility. These results suggest that while alcohol's effects may not be observable in males consuming it, this does not necessarily mean that it has no important biological effects on these males. However, these effects may not be appreciated until their offspring are examined.

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Year:  1991        PMID: 2008415     DOI: 10.1111/j.1600-0773.1991.tb01211.x

Source DB:  PubMed          Journal:  Pharmacol Toxicol        ISSN: 0901-9928


  5 in total

Review 1.  Drinking beyond a lifetime: New and emerging insights into paternal alcohol exposure on subsequent generations.

Authors:  Andrey Finegersh; Gregory R Rompala; David I K Martin; Gregg E Homanics
Journal:  Alcohol       Date:  2015-03-30       Impact factor: 2.405

Review 2.  The impact of exposure to addictive drugs on future generations: Physiological and behavioral effects.

Authors:  F M Vassoler; E M Byrnes; R C Pierce
Journal:  Neuropharmacology       Date:  2013-06-25       Impact factor: 5.250

Review 3.  Alcohol-Induced Developmental Origins of Adult-Onset Diseases.

Authors:  Emilie R Lunde; Shannon E Washburn; Michael C Golding; Shameena Bake; Rajesh C Miranda; Jayanth Ramadoss
Journal:  Alcohol Clin Exp Res       Date:  2016-06-02       Impact factor: 3.455

4.  Reduced alcohol-seeking in male offspring of sires exposed to alcohol self-administration followed by punishment-imposed abstinence.

Authors:  Erin J Campbell; Jeremy P M Flanagan; Nathan J Marchant; Andrew J Lawrence
Journal:  Pharmacol Res Perspect       Date:  2018-02-15

5.  Preconception paternal alcohol exposure exerts sex-specific effects on offspring growth and long-term metabolic programming.

Authors:  Richard C Chang; Haiqing Wang; Yudhishtar Bedi; Michael C Golding
Journal:  Epigenetics Chromatin       Date:  2019-01-22       Impact factor: 4.954

  5 in total

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