Literature DB >> 20083623

Measurement of breathlessness in clinical trials in patients with chronic heart failure: the need for a standardized approach: a systematic review.

Miriam J Johnson1, Stephen G Oxberry, John G F Cleland, Andrew L Clark.   

Abstract

AIMS: Chronic breathlessness is a major symptom for patients with compensated chronic heart failure (CHF) and its impact is different to the breathlessness resulting from pulmonary oedema. This systematic review aims to establish which tools have been used for research into the subjective severity of breathlessness in patients with compensated CHF and to discuss recommendations for the future. METHODS AND
RESULTS: Medline (1950-2008), Embase (1980-2008), Cinahl (1982-2008), and Cochrane databases were searched for clinical studies in patients with compensated CHF including a subjective measure of breathlessness severity as an outcome measure. A total of 322 studies were found of which 41 were retrieved and 26 studies met the review criteria. Few studies had severity of breathlessness as a primary endpoint. Nineteen used a uni-dimensional tool including visual analogue, Borg or Likert scales, either alone, or as a subscale of a quality of life measure. Five used the CHF questionnaire. Two papers used the Baseline Dyspnoea Index-Transitional Dyspnoea Index (BDI-TDI).
CONCLUSION: Despite breathlessness being an important and limiting problem for patients with CHF, we found no consensus on which tool should be used for breathlessness severity, little methodological research to develop such a tool, and a lack of focus on breathlessness as a symptom. A consistent approach to studying breathlessness in patients with CHF is needed in order to make headway in managing this key patient priority.

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Year:  2010        PMID: 20083623     DOI: 10.1093/eurjhf/hfp194

Source DB:  PubMed          Journal:  Eur J Heart Fail        ISSN: 1388-9842            Impact factor:   15.534


  8 in total

1.  A Multidimensional Profile of Dyspnea in Hospitalized Patients.

Authors:  Jennifer P Stevens; Andrew R Sheridan; Heather B Bernstein; Kathy Baker; Robert W Lansing; Richard M Schwartzstein; Robert B Banzett
Journal:  Chest       Date:  2019-05-22       Impact factor: 9.410

2.  An official American Thoracic Society statement: update on the mechanisms, assessment, and management of dyspnea.

Authors:  Mark B Parshall; Richard M Schwartzstein; Lewis Adams; Robert B Banzett; Harold L Manning; Jean Bourbeau; Peter M Calverley; Audrey G Gift; Andrew Harver; Suzanne C Lareau; Donald A Mahler; Paula M Meek; Denis E O'Donnell
Journal:  Am J Respir Crit Care Med       Date:  2012-02-15       Impact factor: 21.405

3.  Reliability, Validity, and Responsiveness of the DEG, a Three-Item Dyspnea Measure.

Authors:  Duc M Ha; Lubin R Deng; Allison V Lange; Jeffrey J Swigris; David B Bekelman
Journal:  J Gen Intern Med       Date:  2022-01-03       Impact factor: 6.473

4.  Assessment of dyspnea early in acute heart failure: patient characteristics and response differences between likert and visual analog scales.

Authors:  Peter S Pang; Sean P Collins; Kori Sauser; Adin-Cristian Andrei; Alan B Storrow; Judd E Hollander; Miguel Tavares; Jindrich Spinar; Cezar Macarie; Dimitar Raev; Richard Nowak; Mihai Gheorghiade; Alexandre Mebazaa
Journal:  Acad Emerg Med       Date:  2014-06       Impact factor: 3.451

Review 5.  Multidimensional Dyspnea Profile: an instrument for clinical and laboratory research.

Authors:  Robert B Banzett; Carl R O'Donnell; Tegan E Guilfoyle; Mark B Parshall; Richard M Schwartzstein; Paula M Meek; Richard H Gracely; Robert W Lansing
Journal:  Eur Respir J       Date:  2015-03-18       Impact factor: 16.671

Review 6.  Reporting of patient-centred outcomes in heart failure trials: are patient preferences being ignored?

Authors:  Jeanet W Blom; Maya El Azzi; Daisy M Wopereis; Liam Glynn; Christiane Muth; Mieke L van Driel
Journal:  Heart Fail Rev       Date:  2015-07       Impact factor: 4.214

7.  Degree of dyspnoea at admission and discharge in patients with heart failure and respiratory diseases.

Authors:  Lourdes Vicent; Juan Manuel Nuñez Olarte; Luis Puente-Maestu; Alicia Oliva; Juan Carlos López; Andrea Postigo; Irene Martín; Raquel Luna; Francisco Fernández-Avilés; Manuel Martínez-Sellés
Journal:  BMC Palliat Care       Date:  2017-05-22       Impact factor: 3.234

8.  Association between lung ultrasound findings and invasive exercise haemodynamics in patients with undifferentiated dyspnoea.

Authors:  Elke Platz; Allison Merz; Montane Silverman; Eldrin Lewis; John D Groarke; Aaron Waxman; David Systrom
Journal:  ESC Heart Fail       Date:  2018-11-26
  8 in total

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