Literature DB >> 20082751

[Progress in treatment of chronic heart failure in Western medicine and treatment strategies in traditional Chinese medicine].

Chang-xun Chen1, Jian-ping Gao, Qi Wu, Juan Guo, Wei-liang Gu.   

Abstract

The concept of modern medicine in treating chronic heart failure (CHF) has changed markedly in recent years. To improve the quality of life and prolong life, the treatment goal is no longer just temporary improvement of symptoms, more importantly, is to prevent and delay the occurrence and development of ventricular remodeling. Long-term chronic over-activation of sympathetic system, renin-angiotensin-aldosterone system and other neuroendocrine factors promotes myocardial remodeling, increases myocardial injury and deteriorates cardiac function. Despite short-term use can significantly improve the blood flow dynamics, long-term use of beta-adrenergic receptor stimulators and phosphodiesterase inhibitors does not prolong life, but increases the rate of sudden death caused by cardiac arrhythmia. Angiotensin converting enzyme inhibitors and beta-blockers have become the preferred drugs in treating chronic heart failure. In fact, after long-term use, beta-blockers can significantly improve ventricular remodeling, enhance ventricular function and reduce the incidence of sudden death of patients with CHF. In traditional Chinese medicine practice, short-term use of drugs for warming yang and reinforcing qi can improve symptoms of CHF, but long-term use may have adverse effects, for these medicines can stimulate sympathetic system. Early treatment with medicines of cold and cool property may be more favorable to patients with CHF, except the advanced patients who need special intervention. Eliminating heat and nourishing yin may play more active role in controlling the occurrence and development of CHF. Drugs with good efficacy and value in treating CHF may be developed from the Chinese herbal medicines with eliminating heat and nourishing yin property.

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Year:  2010        PMID: 20082751     DOI: 10.3736/jcim20100102

Source DB:  PubMed          Journal:  Zhong Xi Yi Jie He Xue Bao        ISSN: 1672-1977


  5 in total

Review 1.  Oral Chinese herbal medicine for improvement of quality of life in patients with chronic heart failure: a systematic review and meta-analysis.

Authors:  Yun-Lun Li; Jian-Qing Ju; Chuan-Hua Yang; Hai-Qiang Jiang; Jing-Wen Xu; Shi-Jun Zhang
Journal:  Qual Life Res       Date:  2013-11-21       Impact factor: 4.147

2.  Yiqi Huoxue Recipe Improves Heart Function through Inhibiting Apoptosis Related to Endoplasmic Reticulum Stress in Myocardial Infarction Model of Rats.

Authors:  Li-Xia Lou; Ai-Ming Wu; Dong-Mei Zhang; Sheng-Xian Wu; Yong-Hong Gao; Bo Nie; Ming-Jing Zhao; Xi-Ying Lv; Qiu-Shuo Jin; Yi-Zhou Zhao; Shuo-Ren Wang; Li-Min Chai
Journal:  Evid Based Complement Alternat Med       Date:  2014-04-17       Impact factor: 2.629

3.  MECHANISMS UNDERLYING ACTION OF XINMAILONG INJECTION, A TRADITIONAL CHINESE MEDICINE IN CARDIAC FUNCTION IMPROVEMENT.

Authors:  Zhengtao Li; Sujuan Li; Lin Hu; Fang Li; Alex Chun Cheung; Weizai Shao; Yuling Que; George Pek-Heng Leung; Cui Yang
Journal:  Afr J Tradit Complement Altern Med       Date:  2017-01-13

4.  Clinical efficacy and safety of Shenqi Fuzheng injection for the treatment of chronic heart failure: Protocol for a meta-analysis and systematic review.

Authors:  Chuan Wang; Dongfeng Yao; Pan Zhang; Xiaowei Xie; Bin Wang; Jiping Liu; Zhen Zhang
Journal:  Medicine (Baltimore)       Date:  2019-12       Impact factor: 1.817

5.  Clinical effects of Xinmailong therapy in patients with chronic heart failure.

Authors:  Qilin Ma; Youxi Luo; Pi Guo; Gan Gao; Meixue Yang; Gaurav Sablok; Yanchun Zhang; Fengfeng Zhou
Journal:  Int J Med Sci       Date:  2013-03-23       Impact factor: 3.738

  5 in total

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