C Celik1, S Altunkan, M O Yildirim, M Akyuz. 1. Department of Physical Medicine and Rehabilitation, Ankara Physical Medicine and Rehabilitation Education and Research Hospital, Ankara, Turkey.
Abstract
OBJECTIVES: The study aimed to compare measurements of coronary artery calcification (CAC) and bone mineral density (BMD) in postmenopausal women. METHODS: The CAC of the women was measured with electron beam tomography using a GE Imatron C150 XP EBT scanner. Subjects with calcium scores above 0 were classified as CAC(+); those without detectable coronary calcium were classified as CAC(-). BMD was measured by dual-energy X-ray absorptiometry (DEXA). Patients were divided into two groups, depending on the T scores of their lumbar spine, into those with normal bone and those with osteopenia-osteoporosis. RESULTS: The proportions of patients classified as CAC(+) were 20% in the normal group and 60% in the osteopenia-osteoporosis group (p = 0.037). BMD values in L1-4 were 1.13 +/- 2.29 and 0.98 +/- 2.79 g/cm(2) in the normal group and osteopenia-osteoporosis group, respectively and the mean total CAC scores were 1.34 +/- 1.2 and 69.0 +/- 20.5, respectively. The CAC scores of patients with osteopenia-osteoporosis were significantly higher compared with those of the normal group (p = 0.014). CONCLUSION: The study shows that postmenopausal women with decreased bone mineral density may have higher risk of subclinical coronary atherosclerosis.
OBJECTIVES: The study aimed to compare measurements of coronary artery calcification (CAC) and bone mineral density (BMD) in postmenopausal women. METHODS: The CAC of the women was measured with electron beam tomography using a GE Imatron C150 XP EBT scanner. Subjects with calcium scores above 0 were classified as CAC(+); those without detectable coronary calcium were classified as CAC(-). BMD was measured by dual-energy X-ray absorptiometry (DEXA). Patients were divided into two groups, depending on the T scores of their lumbar spine, into those with normal bone and those with osteopenia-osteoporosis. RESULTS: The proportions of patients classified as CAC(+) were 20% in the normal group and 60% in the osteopenia-osteoporosis group (p = 0.037). BMD values in L1-4 were 1.13 +/- 2.29 and 0.98 +/- 2.79 g/cm(2) in the normal group and osteopenia-osteoporosis group, respectively and the mean total CAC scores were 1.34 +/- 1.2 and 69.0 +/- 20.5, respectively. The CAC scores of patients with osteopenia-osteoporosis were significantly higher compared with those of the normal group (p = 0.014). CONCLUSION: The study shows that postmenopausal women with decreased bone mineral density may have higher risk of subclinical coronary atherosclerosis.
Authors: J P Beckman; J J Camp; B D Lahr; K R Bailey; A E Kearns; V D Garovic; M Jayachandran; V M Miller; D R Holmes Journal: Climacteric Date: 2017-11-30 Impact factor: 3.005
Authors: Daniela Fodor; Cosmina Bondor; Adriana Albu; Radu Popp; Ioan Victor Pop; Laura Poanta Journal: Indian J Med Res Date: 2013-04 Impact factor: 2.375