Literature DB >> 20081503

The use of systemic hypothermia for the treatment of an acute cervical spinal cord injury in a professional football player.

Andrew Cappuccino1, Leslie J Bisson, Bud Carpenter, John Marzo, W Dalton Dietrich, Helen Cappuccino.   

Abstract

STUDY
DESIGN: Case Report.
OBJECTIVE: We will describe the injury and clinical course of an NFL Football player who sustained a complete spinal cord injury and was treated with conventional care in addition to modest systemic hypothermia. SUMMARY OF BACKGROUND DATA: Systemically induced moderate hypothermia is a potentially neuroprotective intervention in acute spinal cord injury. However, case descriptions of human patients receiving systemic hypothermia after spinal cord injuries are lacking in the literature.
METHODS: Here, we present the case of a National Football League player who sustained a complete (ASIA A) spinal cord injury from a C3/4 fracture dislocation. Moderate systemic hypothermia was instituted immediately after his injury, in addition to standard medical/surgical treatment, including, surgical decompression and intravenous methylprednisolone.
RESULTS: The patient experienced significant and rapid neurologic improvement, and within weeks of his injury was walking with harness assistance. Since that time, the patient has continued to make significant progress in his rehabilitation (now ASIA D).
CONCLUSION: The extent to which this hypothermia contributed to his neurologic recovery is difficult to determine. It is hoped that this case will draw attention to the need for further preclinical and clinical studies to elucidate the role of hypothermia in acute spinal cord injury. Until these studies are completed, it is impossible to advocate for systemic hypothermia as a standard of care.

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Year:  2010        PMID: 20081503     DOI: 10.1097/BRS.0b013e3181b9dc28

Source DB:  PubMed          Journal:  Spine (Phila Pa 1976)        ISSN: 0362-2436            Impact factor:   3.468


  20 in total

1.  Potential long-term benefits of acute hypothermia after spinal cord injury: assessments with somatosensory-evoked potentials.

Authors:  Anil Maybhate; Charles Hu; Faith A Bazley; Qilu Yu; Nitish V Thakor; Candace L Kerr; Angelo H All
Journal:  Crit Care Med       Date:  2012-02       Impact factor: 7.598

2.  Therapeutic systemic hypothermia for a pediatric patient with an isolated cervical spinal cord injury.

Authors:  Jonathan H Pelletier; Courtney H Mann; Benjamin T German; Jefferson G Williams; Mark Piehl
Journal:  J Spinal Cord Med       Date:  2018-09-19       Impact factor: 1.985

Review 3.  Hypothermia for acute brain injury--mechanisms and practical aspects.

Authors:  H Alex Choi; Neeraj Badjatia; Stephan A Mayer
Journal:  Nat Rev Neurol       Date:  2012-02-28       Impact factor: 42.937

Review 4.  Intraoperative Targeted Temperature Management in Acute Brain and Spinal Cord Injury.

Authors:  Jacqueline Kraft; Anna Karpenko; Fred Rincon
Journal:  Curr Neurol Neurosci Rep       Date:  2016-02       Impact factor: 5.081

Review 5.  Hypothermic treatment for acute spinal cord injury.

Authors:  W Dalton Dietrich; Allan D Levi; Michael Wang; Barth A Green
Journal:  Neurotherapeutics       Date:  2011-04       Impact factor: 7.620

6.  Therapeutic hypothermia reduces cortical inflammation associated with utah array implants.

Authors:  Elizabeth A Dugan; Cassie Bennett; Ilmar Tamames; W Dalton Dietrich; Curtis S King; Abhishek Prasad; Suhrud M Rajguru
Journal:  J Neural Eng       Date:  2020-04-29       Impact factor: 5.379

7.  Regional hypothermia inhibits spinal cord somatosensory-evoked potentials without neural damage in uninjured rats.

Authors:  Ning Li; Lei Tian; Wei Wu; Huchen Lu; Yuan Zhou; Xiaoyu Xu; Xiangsheng Zhang; Huilin Cheng; Lihua Zhang
Journal:  J Neurotrauma       Date:  2013-07-16       Impact factor: 5.269

8.  Protection and Repair After Spinal Cord Injury: Accomplishments and Future Directions.

Authors:  W Dalton Dietrich
Journal:  Top Spinal Cord Inj Rehabil       Date:  2015-04-12

9.  A cool approach to reducing electrode-induced trauma: Localized therapeutic hypothermia conserves residual hearing in cochlear implantation.

Authors:  Ilmar Tamames; Curtis King; Esperanza Bas; W Dalton Dietrich; Fred Telischi; Suhrud M Rajguru
Journal:  Hear Res       Date:  2016-05-31       Impact factor: 3.208

10.  Theoretical Evaluation and Experimental Validation of Localized Therapeutic Hypothermia Application to Preserve Residual Hearing After Cochlear Implantation.

Authors:  Ilmar Tamames; Curtis King; Chin-Yuh Huang; Fred F Telischi; Michael E Hoffer; Suhrud M Rajguru
Journal:  Ear Hear       Date:  2018 Jul/Aug       Impact factor: 3.570

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