Literature DB >> 20081230

Nicotine dependence - human and animal studies, current pharmacotherapies and future perspectives.

Magdalena Zaniewska1, Edmund Przegaliński, Małgorzata Filip.   

Abstract

Nicotine dependence is a disease of constantly growing importance. This mini-review describes the effects of nicotine in humans and focuses on the various laboratory animal models developed to study the dependence-related behavioral effects of nicotine. In addition, we outline the current therapeutic approaches designed to substitute nicotine from cigarette smoke with safer compounds or to relieve symptoms of nicotine withdrawal during smoking abstinence. Since several pharmacotherapies have failed to be efficacious in all patients, we also assess the clinical effectiveness of newer agents in relation to existing drugs.

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Year:  2009        PMID： 20081230     DOI： 10.1016/s1734-1140(09)70157-4

Source DB:  PubMed          Journal:  Pharmacol Rep        ISSN： 1734-1140            Impact factor:   3.024


  6 in total

1.  Smoking and red blood cell phospholipid membrane fatty acids.

Authors:  H J Murff; H A Tindle; M J Shrubsole; Q Cai; W Smalley; G L Milne; L L Swift; R M Ness; W Zheng
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2016-08-16       Impact factor: 4.006

Review 2.  Zebrafish for the study of the biological effects of nicotine.

Authors:  Eric W Klee; Jon O Ebbert; Henning Schneider; Richard D Hurt; Stephen C Ekker
Journal:  Nicotine Tob Res       Date:  2011-03-08       Impact factor: 4.244

3.  Repeated administration of the GABAB receptor positive modulator BHF177 decreased nicotine self-administration, and acute administration decreased cue-induced reinstatement of nicotine seeking in rats.

Authors:  Styliani Vlachou; Sebastien Guery; Wolfgang Froestl; Deboshri Banerjee; Jessica Benedict; M G Finn; Athina Markou
Journal:  Psychopharmacology (Berl)       Date:  2010-12-22       Impact factor: 4.530

4.  In vivo modulation of the behavioral effects of nicotine by the coumarins xanthotoxin, bergapten, and umbelliferone.

Authors:  Barbara Budzynska; Krystyna Skalicka-Wozniak; Marta Kruk-Slomka; Malgorzata Wydrzynska-Kuzma; Grazyna Biala
Journal:  Psychopharmacology (Berl)       Date:  2016-04-14       Impact factor: 4.530

5.  Influence of acute or chronic calcium channel antagonists on the acquisition and consolidation of memory and nicotine-induced cognitive effects in mice.

Authors:  Grazyna Biala; Marta Kruk-Slomka; Krzysztof Jozwiak
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2013-04-12       Impact factor: 3.000

6.  Animal models of nicotine exposure: relevance to second-hand smoking, electronic cigarette use, and compulsive smoking.

Authors:  Ami Cohen; Olivier George
Journal:  Front Psychiatry       Date:  2013-06-04       Impact factor: 4.157
  6 in total

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