Literature DB >> 20080082

Effect of different calcineurin inhibitors on AOPP and TAS after kidney transplantation.

Josef Zadrazil1, Pavel Strebl, Karel Krejcí, Vladko Horcicka, Pavel Horák, Jitka Vostálová, Adéla Zdarilová, Markéta Kajabová, Petr Schneiderka.   

Abstract

OBJECTIVES: Little is known about the influence of calcineurin inhibitors on advanced oxidation protein products (AOPP) and total antioxidant status (TAS) after renal transplantation. DESIGN AND METHODS: AOPP and TAS were evaluated in transplanted patients on different calcineurin inhibitors. Thirty-five patients were treated with cyclosporine A (group A) and 33 with tacrolimus (group B).
RESULTS: Over 6 months, the mean levels of AOPP in group A decreased from 205.9+/-125.7 to 140.9+/-78.9 micromol/L and TAS from 1.89+/-0.30 to 1.75+/-0.27 mmol/L. In group B, the mean levels of AOPP decreased from 196.5+/-123.9 to 129.6+/-63.8 micromol/L and TAS from 1.80+/-0.39 to 1.78+/-0.23 mmol/L.
CONCLUSION: No significant differences in AOPP and TAS were found with respect to treatment. The only exception was the higher mean concentration of AOPP at month 1 in group A (p=0.026). Copyright 2010 The Canadian Society of Clinical Chemists. Published by Elsevier Inc. All rights reserved.

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Year:  2010        PMID： 20080082     DOI： 10.1016/j.clinbiochem.2010.01.003

Source DB:  PubMed          Journal:  Clin Biochem        ISSN： 0009-9120            Impact factor:   3.281


  5 in total

1.  Gender differences in oxidative and nitrosative stress parameters in kidney transplant patients on tacrolimus-based immunosuppression.

Authors:  Tatjana P Cvetkovic; Nikola Z Stefanovic; Radmila M Velickovic-Radovanovic; Goran J Paunovic; Vidojko M Djordjevic; Dijana R Stojanovic; Ivana R Stojanovic; Dusica D Pavlovic
Journal:  Int Urol Nephrol       Date:  2013-10-08       Impact factor: 2.370

2.  Pharmacogenetics may Influence Tacrolimus Daily Dose, but not Urinary Tubular Damage Markers in the Long-Term Period after Renal Transplantation.

Authors:  Nikola Z Stefanović; Tatjana P Cvetković; Radmila M Veličković-Radovanović; Tatjana M Jevtović-Stoimenov; Predrag M Vlahović; Ivana R Stojanović; Dušica D Pavlović
Journal:  J Med Biochem       Date:  2015-09-19       Impact factor: 3.402

3.  Oxidative and Nitrosative Stress in Stable Renal Transplant Recipients with Respect to the Immunosuppression Protocol - Differences or Similarities?

Authors:  Tatjana Cvetković; Radmila Veličković-Radovanović; Dijana Stojanović; Nikola Stefanović; Aleksandra Ignjatović; Ivana Stojanović; Nikola Sladojević; Dušica Pavlović
Journal:  J Med Biochem       Date:  2015-07-14       Impact factor: 3.402

Review 4.  Effect of Calcineurin Inhibitors and Mammalian Target of Rapamycin Inhibitors on the Course of COVID-19 in Kidney Transplant Recipients.

Authors:  Nuri Baris Hasbal; Didem Turgut; Ebru Gok Oguz; Sena Ulu; Ozkan Gungor
Journal:  Ann Transplant       Date:  2021-03-12       Impact factor: 1.530

Review 5.  Potential Effects of Immunosuppression on Oxidative Stress and Atherosclerosis in Kidney Transplant Recipients.

Authors:  Marlena Kwiatkowska; Urszula Oldakowska-Jedynak; Ewa Wojtaszek; Tomasz Glogowski; Jolanta Malyszko
Journal:  Oxid Med Cell Longev       Date:  2021-02-20       Impact factor: 6.543
  5 in total

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