Literature DB >> 20079756

Nrf2 in toxicology and pharmacology: the good, the bad and the ugly?

Jingbo Pi, Michael L Freeman, Masayuki Yamamoto.   

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Year:  2010        PMID： 20079756      PMCID： PMC2837784          DOI： 10.1016/j.taap.2010.01.005

Source DB:  PubMed          Journal:  Toxicol Appl Pharmacol        ISSN： 0041-008X            Impact factor:   4.219


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  34 in total

1.  Nrf2 is essential for protection against acute pulmonary injury in mice.

Authors:  K Chan; Y W Kan
Journal:  Proc Natl Acad Sci U S A       Date:  1999-10-26       Impact factor: 11.205

2.  Distinct cysteine residues in Keap1 are required for Keap1-dependent ubiquitination of Nrf2 and for stabilization of Nrf2 by chemopreventive agents and oxidative stress.

Authors:  Donna D Zhang; Mark Hannink
Journal:  Mol Cell Biol       Date:  2003-11       Impact factor: 4.272

3.  Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.

Authors:  M Ramos-Gomez; M K Kwak; P M Dolan; K Itoh; M Yamamoto; P Talalay; T W Kensler
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

4.  Impaired expression of glutathione synthetic enzyme genes in mice with targeted deletion of the Nrf2 basic-leucine zipper protein.

Authors:  J Y Chan; M Kwong
Journal:  Biochim Biophys Acta       Date:  2000-12-15

5.  An important function of Nrf2 in combating oxidative stress: detoxification of acetaminophen.

Authors:  K Chan; X D Han; Y W Kan
Journal:  Proc Natl Acad Sci U S A       Date:  2001-04-03       Impact factor: 11.205

Review 6.  Integration and diversity of the regulatory network composed of Maf and CNC families of transcription factors.

Authors:  Hozumi Motohashi; Tania O'Connor; Fumiki Katsuoka; James Douglas Engel; Masayuki Yamamoto
Journal:  Gene       Date:  2002-07-10       Impact factor: 3.688

7.  Nrf2 transcription factor, a novel target of keratinocyte growth factor action which regulates gene expression and inflammation in the healing skin wound.

Authors:  Susanne Braun; Christine Hanselmann; Marcus G Gassmann; Ulrich auf dem Keller; Christiane Born-Berclaz; Kaimin Chan; Yuet Wai Kan; Sabine Werner
Journal:  Mol Cell Biol       Date:  2002-08       Impact factor: 4.272

8.  Erythroid transcription factor NF-E2 is a haematopoietic-specific basic-leucine zipper protein.

Authors:  N C Andrews; H Erdjument-Bromage; M B Davidson; P Tempst; S H Orkin
Journal:  Nature       Date:  1993-04-22       Impact factor: 49.962

Review 9.  Nrf2 protects against airway disorders.

Authors:  Hye-Youn Cho; Steven R Kleeberger
Journal:  Toxicol Appl Pharmacol       Date:  2009-07-29       Impact factor: 4.219

10.  Complexity of CNC transcription factors as revealed by gene targeting of the Nrf3 locus.

Authors:  Anna Derjuga; Tania S Gourley; Teresa M Holm; Henry H Q Heng; Ramesh A Shivdasani; Rafi Ahmed; Nancy C Andrews; Volker Blank
Journal:  Mol Cell Biol       Date:  2004-04       Impact factor: 4.272
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  8 in total

Review 1.  Persistent polar depletion of stratospheric ozone and emergent mechanisms of ultraviolet radiation-mediated health dysregulation.

Authors:  Mark A Dugo; Fengxiang Han; Paul B Tchounwou
Journal:  Rev Environ Health       Date:  2012       Impact factor: 3.458

2.  Nrf1 CNC-bZIP protein promotes cell survival and nucleotide excision repair through maintaining glutathione homeostasis.

Authors:  Weinong Han; Mei Ming; Rui Zhao; Jingbo Pi; Chunli Wu; Yu-Ying He
Journal:  J Biol Chem       Date:  2012-04-12       Impact factor: 5.157

3.  Conditioned media of choroid plexus epithelial cells induces Nrf2-activated phase II antioxidant response proteins and suppresses oxidative stress-induced apoptosis in PC12 cells.

Authors:  Abbas Aliaghaei; Fariba Khodagholi; Abolhassan Ahmadiani
Journal:  J Mol Neurosci       Date:  2014-02-04       Impact factor: 3.444

4.  Beyond antioxidant genes in the ancient Nrf2 regulatory network.

Authors:  Sarah E Lacher; Joslynn S Lee; Xuting Wang; Michelle R Campbell; Douglas A Bell; Matthew Slattery
Journal:  Free Radic Biol Med       Date:  2015-07-08       Impact factor: 7.376

5.  Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes.

Authors:  Baozhong Zhao; Palak Shah; Lei Qiang; Tong-Chuan He; Andrey Budanov; Yu-Ying He
Journal:  Photochem Photobiol       Date:  2016-08-12       Impact factor: 3.421

6.  Mercuric compounds induce pancreatic islets dysfunction and apoptosis in vivo.

Authors:  Kuo-Liang Chen; Shing-Hwa Liu; Chin-Chuan Su; Cheng-Chieh Yen; Ching-Yao Yang; Kuan-I Lee; Feng-Cheng Tang; Ya-Wen Chen; Tien-Hui Lu; Yi-Chang Su; Chun-Fa Huang
Journal:  Int J Mol Sci       Date:  2012-09-26       Impact factor: 5.923

7.  Expression of metallothionein and Nrf2 pathway genes in lung cancer and cancer-surrounding tissues.

Authors:  Gui-You Liang; Sheng-Xun Lu; Gang Xu; Xing-Da Liu; Jian Li; Deng-Shen Zhang
Journal:  World J Surg Oncol       Date:  2013-08-16       Impact factor: 2.754

Review 8.  Pathogenic Mechanisms of Myeloma Bone Disease and Possible Roles for NRF2.

Authors:  Chia-Hung Yen; Chin-Mu Hsu; Samuel Yien Hsiao; Hui-Hua Hsiao
Journal:  Int J Mol Sci       Date:  2020-09-14       Impact factor: 5.923
  8 in total

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