Literature DB >> 20077136

Uncommon pediatric painless scrotal masses: a puzzle of pediatricians and urologists.

Xingang Yuan1, Guanghui Wei, Tao Lin, Dawei He, Xuliang Li.   

Abstract

OBJECTIVE: A broad spectrum of scrotal pathologies, including tumors, malformations, and inflammation, can present as painless scrotal masses in the pediatric age groups. The aim of our single institutional retrospective study was to survey data regarding uncommon painless scrotal masses collected over the past 22 years in order to better diagnose and treat these pathologies. PATIENTS AND METHODS: This retrospective study included children referred to our hospital because of scrotal masses between October 1986 and May 2009. In all cases, age at diagnosis, history, and physical examination details, biochemical markers, and findings of imaging were collected and analyzed. Definite diagnoses of the causes of the scrotal masses were made through histopathological examination.
RESULTS: A total of 161 children were examined because of scrotal masses during the study period. Their ages ranged from 1 month and 2 days to 14 years and 9 months (median, 2 years 11 months). Bilateral scrotal masses were observed in 17 cases. Of 161 scrotal masses, 119 (73.9%) originated from testes, 27 (16.8%) from epididymis, and 15 (9.3%) from the scrotal wall. Of these, 116 (72%) were diagnosed as tumors, 22 (13.7%) as malformations, and 23 (14.3%) as inflammation. Fourteen patients had misdiagnosed histories; of these, the majority (11) were diagnosed with yolk-sac tumors.
CONCLUSIONS: Although testicular tumors are the major causes of pediatric painless scrotal masses, other causes are possible. Patient history and physical examination can provide some clues as to the source of the mass. Ultrasound, alpha-fetoprotein levels, and biochemical analysis have a significant role in the evaluation of uncommon pediatric painless scrotal masses.

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Year:  2010        PMID: 20077136     DOI: 10.1007/s11255-010-9704-0

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  17 in total

Review 1.  Sonography of the scrotum.

Authors:  Vikram S Dogra; Ronald H Gottlieb; Mayumi Oka; Deborah J Rubens
Journal:  Radiology       Date:  2003-02-28       Impact factor: 11.105

2.  Prepubertal Testicular Tumor Registry.

Authors:  R Kay
Journal:  J Urol       Date:  1993-08       Impact factor: 7.450

3.  Painless scrotal swelling: ultrasonographical features with pathological correlation.

Authors:  M Muttarak; B Chaiwun
Journal:  Singapore Med J       Date:  2005-04       Impact factor: 1.858

4.  Gray-scale and color Doppler sonography of scrotal disorders in children: an update.

Authors:  Celestino Aso; Goya Enríquez; Marta Fité; Nuria Torán; Carmen Piró; Joaquim Piqueras; Javier Lucaya
Journal:  Radiographics       Date:  2005 Sep-Oct       Impact factor: 5.333

5.  Incidence of testicular germ-cell malignancies in England and Wales: trends in children compared with adults.

Authors:  I dos Santos Silva; A J Swerdlow; C A Stiller; A Reid
Journal:  Int J Cancer       Date:  1999-11-26       Impact factor: 7.396

Review 6.  Yolk sac tumors and alpha-fetoprotein in first year of life.

Authors:  J A Brewer; E S Tank
Journal:  Urology       Date:  1993-07       Impact factor: 2.649

7.  Epidemiological and clinical behavior of prepubertal testicular tumors in Korea.

Authors:  Sang Don Lee
Journal:  J Urol       Date:  2004-08       Impact factor: 7.450

8.  Pediatric testicular tumors: contemporary incidence and efficacy of testicular preserving surgery.

Authors:  Peter D Metcalfe; H Farivar-Mohseni; Walid Farhat; Gordon McLorie; Antoine Khoury; Darius J Bägli
Journal:  J Urol       Date:  2003-12       Impact factor: 7.450

9.  Clinical behavior and a contemporary management algorithm for prepubertal testis tumors: a summary of the Prepubertal Testis Tumor Registry.

Authors:  Jonathan H Ross; Lisa Rybicki; Robert Kay
Journal:  J Urol       Date:  2002-10       Impact factor: 7.450

10.  Ultrasonography of intratesticular lesions: its role in clinical management.

Authors:  P T Kennedy; J M Elliott; P F Rice; B E Kelly
Journal:  Ulster Med J       Date:  1999-11
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  1 in total

Review 1.  Benign penile skin anomalies in children: a primer for pediatricians.

Authors:  Marco Castagnetti; Mike Leonard; Luis Guerra; Ciro Esposito; Marcello Cimador
Journal:  World J Pediatr       Date:  2015-03-09       Impact factor: 2.764

  1 in total

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