Literature DB >> 2007239

Blood lead levels in children and pregnant women living near a lead-reclamation plant.

P Levallois1, M Lavoie, L Goulet, A J Nantel, S Gingras.   

Abstract

OBJECTIVE: To determine the effect of lead contamination around a lead-reclamation plant on the blood lead levels of children and pregnant women living in the area.
DESIGN: Prevalence study.
SETTING: Residents living 150 m or less (high-exposure area), 151 to 400 m (intermediate-exposure area) or 401 to 800 m (low-exposure area) southeast from the plant. PARTICIPANTS: All children aged 10 years or less and all pregnant women living in the designated area. OUTCOME MEASURES: Correlation of venous blood lead levels with soil lead concentrations in the areas in which the subjects lived and with sociodemographic and behavioural factors. MAIN
RESULTS: Of the estimated 57 pregnant women 38 (67%) participated: 20 were in the high-exposure area and 18 in the other two areas; their geometric mean blood lead levels were low (0.15 and 0.13 mumol/L respectively). Of the 625 eligible children 510 (82%) participated: 169 were in the high-exposure area, 179 in the intermediate-exposure area and 162 in the low-exposure area; their geometric mean lead levels were 0.43, 0.30 and 0.26 mumol/L respectively. Within each age group children in the high-exposure area had the highest levels. The mean levels for children aged 6 months to 5 years were 0.49, 0.35 and 0.28 mumol/L in the three areas respectively. Within each exposure group children aged 1 to 2 years had the highest levels. No potential confounding variables could explain the relation between blood lead level and soil lead concentration.
CONCLUSIONS: The pregnant women's blood lead levels did not seem to be affected by exposure level, but the children's levels were primarily related to the soil lead concentration.

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Year:  1991        PMID: 2007239      PMCID: PMC1335285     

Source DB:  PubMed          Journal:  CMAJ        ISSN: 0820-3946            Impact factor:   8.262


  20 in total

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Authors:  I B Millar
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