Literature DB >> 20072136

Cathepsin S elicits itch and signals via protease-activated receptors.

Vemuri B Reddy, Steven G Shimada, Parul Sikand, Robert H Lamotte, Ethan A Lerner.   

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Year:  2010        PMID: 20072136      PMCID: PMC2855395          DOI: 10.1038/jid.2009.430

Source DB:  PubMed          Journal:  J Invest Dermatol        ISSN: 0022-202X            Impact factor:   8.551


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  17 in total

1.  Agonists of proteinase-activated receptor 2 induce inflammation by a neurogenic mechanism.

Authors:  M Steinhoff; N Vergnolle; S H Young; M Tognetto; S Amadesi; H S Ennes; M Trevisani; M D Hollenberg; J L Wallace; G H Caughey; S E Mitchell; L M Williams; P Geppetti; E A Mayer; N W Bunnett
Journal:  Nat Med       Date:  2000-02       Impact factor: 53.440

Review 2.  The neurobiology of itch.

Authors:  Akihiko Ikoma; Martin Steinhoff; Sonja Ständer; Gil Yosipovitch; Martin Schmelz
Journal:  Nat Rev Neurosci       Date:  2006-07       Impact factor: 34.870

3.  Kallikrein-mediated cell signalling: targeting proteinase-activated receptors (PARs).

Authors:  Katerina Oikonomopoulou; Kristina K Hansen; Mahmoud Saifeddine; Nathalie Vergnolle; Illa Tea; Michael Blaber; Sachiko I Blaber; Isobel Scarisbrick; Eleftherios P Diamandis; Morley D Hollenberg
Journal:  Biol Chem       Date:  2006-06       Impact factor: 3.915

4.  Secreted cathepsin L generates endostatin from collagen XVIII.

Authors:  U Felbor; L Dreier; R A Bryant; H L Ploegh; B R Olsen; W Mothes
Journal:  EMBO J       Date:  2000-03-15       Impact factor: 11.598

5.  House dust mite allergens induce proinflammatory cytokines from respiratory epithelial cells: the cysteine protease allergen, Der p 1, activates protease-activated receptor (PAR)-2 and inactivates PAR-1.

Authors:  Nithiananthan Asokananthan; Peter T Graham; David J Stewart; Anthony J Bakker; Karin A Eidne; Philip J Thompson; Geoffrey A Stewart
Journal:  J Immunol       Date:  2002-10-15       Impact factor: 5.422

6.  Impaired invariant chain degradation and antigen presentation and diminished collagen-induced arthritis in cathepsin S null mice.

Authors:  T Y Nakagawa; W H Brissette; P D Lira; R J Griffiths; N Petrushova; J Stock; J D McNeish; S E Eastman; E D Howard; S R Clarke; E F Rosloniec; E A Elliott; A Y Rudensky
Journal:  Immunity       Date:  1999-02       Impact factor: 31.745

7.  Cathepsin S activity is detectable in human keratinocytes and is selectively upregulated upon stimulation with interferon-gamma.

Authors:  Gerold Schwarz; Wolf-Henning Boehncke; Manuela Braun; Christian J Schröter; Timo Burster; Thomas Flad; Daniela Dressel; Ekkehard Weber; Heide Schmid; Hubert Kalbacher
Journal:  J Invest Dermatol       Date:  2002-07       Impact factor: 8.551

8.  Separate peripheral pathways for pruritus in man.

Authors:  Barbara Namer; Richard Carr; Lisa M Johanek; Martin Schmelz; Hermann O Handwerker; Matthias Ringkamp
Journal:  J Neurophysiol       Date:  2008-06-18       Impact factor: 2.714

9.  Proteinase-activated receptor-2 mediates itch: a novel pathway for pruritus in human skin.

Authors:  Martin Steinhoff; Ulrich Neisius; Akihiko Ikoma; Manigé Fartasch; Gisela Heyer; Per S Skov; Thomas A Luger; Martin Schmelz
Journal:  J Neurosci       Date:  2003-07-16       Impact factor: 6.167

10.  A role for polymodal C-fiber afferents in nonhistaminergic itch.

Authors:  Lisa M Johanek; Richard A Meyer; Robert M Friedman; Kenneth W Greenquist; Beom Shim; Jasenka Borzan; Tim Hartke; Robert H LaMotte; Matthias Ringkamp
Journal:  J Neurosci       Date:  2008-07-23       Impact factor: 6.167

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  42 in total

1.  Pruriceptive spinothalamic tract neurons: physiological properties and projection targets in the primate.

Authors:  Steve Davidson; Xijing Zhang; Sergey G Khasabov; Hannah R Moser; Christopher N Honda; Donald A Simone; Glenn J Giesler
Journal:  J Neurophysiol       Date:  2012-06-20       Impact factor: 2.714

Review 2.  Mediators of Chronic Pruritus in Atopic Dermatitis: Getting the Itch Out?

Authors:  Nicholas K Mollanazar; Peter K Smith; Gil Yosipovitch
Journal:  Clin Rev Allergy Immunol       Date:  2016-12       Impact factor: 8.667

Review 3.  Cysteine cathepsins: their role in tumor progression and recent trends in the development of imaging probes.

Authors:  Reik Löser; Jens Pietzsch
Journal:  Front Chem       Date:  2015-06-23       Impact factor: 5.221

4.  Cathepsin S is activated during colitis and causes visceral hyperalgesia by a PAR2-dependent mechanism in mice.

Authors:  Fiore Cattaruzza; Victoria Lyo; Ella Jones; David Pham; James Hawkins; Kimberley Kirkwood; Eduardo Valdez-Morales; Charles Ibeakanma; Stephen J Vanner; Matthew Bogyo; Nigel W Bunnett
Journal:  Gastroenterology       Date:  2011-07-28       Impact factor: 22.682

Review 5.  Basic mechanisms of itch.

Authors:  C Potenzieri; B J Undem
Journal:  Clin Exp Allergy       Date:  2011-06-06       Impact factor: 5.018

Review 6.  Mouse models of acute, chemical itch and pain in humans.

Authors:  Robert H LaMotte; Steven G Shimada; Parul Sikand
Journal:  Exp Dermatol       Date:  2011-10       Impact factor: 3.960

Review 7.  Trp channels and itch.

Authors:  Shuohao Sun; Xinzhong Dong
Journal:  Semin Immunopathol       Date:  2015-09-18       Impact factor: 9.623

Review 8.  Itch mechanisms and circuits.

Authors:  Liang Han; Xinzhong Dong
Journal:  Annu Rev Biophys       Date:  2014       Impact factor: 12.981

9.  PAR2 Pepducin-Based Suppression of Inflammation and Itch in Atopic Dermatitis Models.

Authors:  Travis P Barr; Chris Garzia; Srijoy Guha; Elizabeth K Fletcher; Nga Nguyen; Adam J Wieschhaus; Lluis Ferrer; Lidija Covic; Athan Kuliopulos
Journal:  J Invest Dermatol       Date:  2018-10-01       Impact factor: 8.551

10.  Cathepsin S silencing induces apoptosis of human hepatocellular carcinoma cells.

Authors:  Xuedi Wang; Li Xiong; Guotang Yu; Dongdong Li; Tao Peng; Daqing Luo; Jing Xu
Journal:  Am J Transl Res       Date:  2015-01-19       Impact factor: 4.060

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