Literature DB >> 20070498

Owner's perception of carboplatin in conjunction with other palliative treatments for cancer therapy.

D B Bowles1, M C Robson, P E Galloway, L Walker.   

Abstract

OBJECTIVES: To determine owner's perception of their pet's quality of life during treatment with carboplatin for a variety of canine and feline neoplasms.
METHODS: Owners were contacted via a postal questionnaire and asked questions regarding their perception of chemotherapy in pets and their perception of carboplatin treatment in their pet.
RESULTS: Twenty-eight (59%) of owners responded to the questionnaire. Forty-three percent of owners had not considered chemotherapy in pets before treatment; however, after treatment, 89% of owners supported its use. Sixteen (57%) patients had mild to severe side effects. Most patients experienced mild side effects, including lethargy and loss of appetite. Quality of life during treatment was reduced compared with prediagnosis quality of life however at its best was significantly improved compared with pretreatment quality of life. Eighty-nine per cent of respondents did not regret treating their pet. CLINICAL SIGNIFICANCE: Carboplatin is well tolerated by both owners and pets. Most patients have either no side effects or experience mild lethargy or inappetence. Carboplatin treatment, either alone or in conjunction with other medications, should be considered as a palliative treatment in both dogs and cats with susceptible neoplasms.

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Year:  2010        PMID: 20070498     DOI: 10.1111/j.1748-5827.2009.00891.x

Source DB:  PubMed          Journal:  J Small Anim Pract        ISSN: 0022-4510            Impact factor:   1.522


  4 in total

Review 1.  Species differences in tumour responses to cancer chemotherapy.

Authors:  Jessica Lawrence; David Cameron; David Argyle
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2015-07-19       Impact factor: 6.237

2.  Plasma Cytokeratin 18 and fecal Alpha-1 Antitrypsin concentrations in dogs with osteosarcoma receiving carboplatin chemotherapy.

Authors:  Kathryn Taikowski; Adam J Rudinsky; Darian S Louke; Emma Warry; Joelle M Fenger
Journal:  Vet Med Sci       Date:  2020-11-22

3.  Quality of life assessment in cancer patients receiving single-agent versus multidrug chemotherapy protocols.

Authors:  Marco Luigi Bianchi; Dario Drudi; Elisabetta Treggiari; Chiara Catalucci; Valeria Attorri; Irene Bonazzi; Paola Valenti
Journal:  Open Vet J       Date:  2021-12-05

Review 4.  Quality of life measurement in prospective studies of cancer treatments in dogs and cats.

Authors:  M A Giuffrida; S M Kerrigan
Journal:  J Vet Intern Med       Date:  2014-10-10       Impact factor: 3.333

  4 in total

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