OBJECTIVES: To evaluate the outcome of different techniques of urethroplasty and to assess the quality of an in-home algorithm. METHODS: Two hundred fifty-two male patients underwent urethroplasty. Mean patient's age was 48 years (range 1-85 years). Data were analyzed for the failure rate of the different techniques of urethroplasty. An additional analysis was done based on an in-home algorithm. RESULTS: Median follow up was 37 months (range: 6-92 months). Global failure rate was 14.9%, with an individual failure rate of 11.7%, 16.0%, 20.7% and 20.8% for anastomotic repair, free graft urethroplasty, pedicled flap urethroplasty and combined urethroplasty, respectively. In free graft urethroplasty, results were significantly worse when extrapreputial skin was used. Anastomotic repair was the principle technique for short strictures (83.3%), at the bulbar and posterior urethra (respectively 50.8 and 100%). Free graft urethroplasty was mainly used for 3-10 cm strictures (58.6%). Anastomotic repair and free graft urethroplasty were more used in case of no previous interventions or after urethrotomy/dilation. Pedicled flap urethroplasty was the main technique at the penile urethra (40.7%). Combined urethroplasty was necessary in 41 and 47.1% in the treatment of, respectively, >10 cm or panurethral/multifocal anterior urethral strictures and was the most important technique in these circumstances. Two-stage urethroplasty or perineostomy were only used in 2% as first-line treatment but were already used in 14.9% after failed urethroplasty. CONCLUSION: Urethroplasty has good results at intermediate follow up. Different types of techniques must be used for different types of strictures.
OBJECTIVES: To evaluate the outcome of different techniques of urethroplasty and to assess the quality of an in-home algorithm. METHODS: Two hundred fifty-two male patients underwent urethroplasty. Mean patient's age was 48 years (range 1-85 years). Data were analyzed for the failure rate of the different techniques of urethroplasty. An additional analysis was done based on an in-home algorithm. RESULTS: Median follow up was 37 months (range: 6-92 months). Global failure rate was 14.9%, with an individual failure rate of 11.7%, 16.0%, 20.7% and 20.8% for anastomotic repair, free graft urethroplasty, pedicled flap urethroplasty and combined urethroplasty, respectively. In free graft urethroplasty, results were significantly worse when extrapreputial skin was used. Anastomotic repair was the principle technique for short strictures (83.3%), at the bulbar and posterior urethra (respectively 50.8 and 100%). Free graft urethroplasty was mainly used for 3-10 cm strictures (58.6%). Anastomotic repair and free graft urethroplasty were more used in case of no previous interventions or after urethrotomy/dilation. Pedicled flap urethroplasty was the main technique at the penile urethra (40.7%). Combined urethroplasty was necessary in 41 and 47.1% in the treatment of, respectively, >10 cm or panurethral/multifocal anterior urethral strictures and was the most important technique in these circumstances. Two-stage urethroplasty or perineostomy were only used in 2% as first-line treatment but were already used in 14.9% after failed urethroplasty. CONCLUSION: Urethroplasty has good results at intermediate follow up. Different types of techniques must be used for different types of strictures.
Authors: Javier Tinaut-Ranera; Miguel Ángel Arrabal-Polo; Sergio Merino-Salas; Mercedes Nogueras-Ocaña; Víctor Manuel López-León; Francisco Palao-Yago; Miguel Arrabal-Martín; Clara Lahoz-García; Miguel Alaminos; Armando Zuluaga-Gomez Journal: Can Urol Assoc J Date: 2014 Jan-Feb Impact factor: 1.862
Authors: Nicolaas Lumen; Matthias Beysens; Charles Van Praet; Karel Decaestecker; Anne-Francoise Spinoit; Piet Hoebeke; Willem Oosterlinck Journal: Biomed Res Int Date: 2015-02-19 Impact factor: 3.411
Authors: Kaile Zhang; Jun Chen; Dongliang Zhang; Lin Wang; Weixin Zhao; David Yun-Te Lin; Rong Chen; Hong Xie; Xiaoyong Hu; Xiaolan Fang; Qiang Fu Journal: Int J Mol Med Date: 2018-02-12 Impact factor: 4.101