P K Eide1, E-H Park, J R Madsen. 1. Department of Neurosurgery, Division of Clinical Neuroscience, Rikshospitalet University Hospital, Oslo, Norway. per.kristian.eide@rikshospitalet.no
Abstract
OBJECTIVE: To characterize the association between arterial blood pressure (ABP) and intracranial pressure (ICP) in idiopathic normal pressure hydrocephalus (iNPH) patients, and its impact on outcome of shunt surgery. MATERIALS AND METHODS: We analyzed all 35 iNPH patients whose ABP and ICP were recorded simultaneously during 6 years (2002-2007). The static and pulsatile pressures were averaged over consecutive 6-s intervals; the moving correlations between ICP and ABP (static and pulsatile) were determined during consecutive 4-min periods to explore time-related variations. RESULTS: Neither static nor pulsatile ABP were altered in iNPH shunt responders. Elevated pulsatile ICP, but normal static ICP, was seen in responders. The time-varying correlations of static and of pulsatile pressures were generally low, and did not differ between shunt responders/non-responders. CONCLUSIONS: In iNPH shunt responders, static or pulsatile ABP were not altered and only pulsatile ICP was elevated.
OBJECTIVE: To characterize the association between arterial blood pressure (ABP) and intracranial pressure (ICP) in idiopathic normal pressure hydrocephalus (iNPH) patients, and its impact on outcome of shunt surgery. MATERIALS AND METHODS: We analyzed all 35 iNPH patients whose ABP and ICP were recorded simultaneously during 6 years (2002-2007). The static and pulsatile pressures were averaged over consecutive 6-s intervals; the moving correlations between ICP and ABP (static and pulsatile) were determined during consecutive 4-min periods to explore time-related variations. RESULTS: Neither static nor pulsatile ABP were altered in iNPH shunt responders. Elevated pulsatile ICP, but normal static ICP, was seen in responders. The time-varying correlations of static and of pulsatile pressures were generally low, and did not differ between shunt responders/non-responders. CONCLUSIONS: In iNPH shunt responders, static or pulsatile ABP were not altered and only pulsatile ICP was elevated.
Authors: D K Radolovich; M J H Aries; G Castellani; A Corona; A Lavinio; P Smielewski; J D Pickard; M Czosnyka Journal: Neurocrit Care Date: 2011-12 Impact factor: 3.210
Authors: Danilo Cardim; Bernhard Schmidt; Chiara Robba; Joseph Donnelly; Corina Puppo; Marek Czosnyka; Peter Smielewski Journal: Neurocrit Care Date: 2017-06 Impact factor: 3.210
Authors: Santhosh G Thavarajasingam; Mahmoud El-Khatib; Mark Rea; Salvatore Russo; Johannes Lemcke; Lana Al-Nusair; Peter Vajkoczy Journal: Acta Neurochir (Wien) Date: 2021-07-08 Impact factor: 2.216