Literature DB >> 200698

The interaction of Herpes Simplex Virus with murine lymphocytes. I. Mitogenic properties of herpes simplex virus.

D Mochizuki, S Hedrick, J Watson, D T Kingsbury.   

Abstract

Herpes simplex virus (HSV) stimulates DNA synthesis in mouse spleen cultures prepared from normal, macrophage-depleted, and T-cell-depleted spleen cells, but not from thymocytes. In addition, a polyclonal antibody response is observed in HSV-infected spleen cultures. These findings indicate that the cells stimulated to undergo DNA synthesis after HSV infection appear to be the bone marrow-derived lymphocytes. The newly synthesized DNA is host cell and not of viral origin. Heat treatment and ultraviolet irradiation of HSV before addition to spleen cultures prevents the induction of DNA synthesis. We consider the use of this system as assay for the study of cell transformation by HSV and also for the study of host cell control of the expression of the viral genome.

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Year:  1977        PMID： 200698      PMCID： PMC2181902          DOI： 10.1084/jem.146.6.1500

Source DB:  PubMed          Journal:  J Exp Med        ISSN： 0022-1007            Impact factor:   14.307


  22 in total

1.  Presence of chicken tumour virus in the sarcoma of the adult rat inoculated after birth with Rous sarcoma tissue.

Authors:  J SVOBODA
Journal:  Nature       Date:  1960-06-18       Impact factor: 49.962

2.  Herpes simplex viruses: discrimination of types and correlation between different characteristics.

Authors:  G Plummer; C R Goodheart; M Miyagi; G R Skinner; M E Thouless; P Wildy
Journal:  Virology       Date:  1974-07       Impact factor: 3.616

3.  Human embryonic lung cells abortively infected with Herpes virus hominis type 2 show some properties of cell transformation.

Authors:  G Darai; K Munk
Journal:  Nat New Biol       Date:  1973-02-28

4.  Oncogenic transformation of hamster cells after exposure to herpes simplex virus type 2.

Authors:  R Duff; F Rapp
Journal:  Nat New Biol       Date:  1971-09-08

Review 5.  Aspects of the EB virus.

Authors:  M A Epstein
Journal:  Adv Cancer Res       Date:  1970       Impact factor: 6.242

6.  Sarcomas after inoculation of newborn hamsters with Herpes virus hominis type 2 strains.

Authors:  A J Nahmias; Z M Naib; W E Josey; F A Murphy; C F Luce
Journal:  Proc Soc Exp Biol Med       Date:  1970-09

7.  Association of antigenic type of Herpesvirus hominis with site of viral recovery.

Authors:  W R Dowdle; A J Nahmias; R W Harwell; F P Pauls
Journal:  J Immunol       Date:  1967-11       Impact factor: 5.422

8.  Oncogenic transformation of hamster embryo cells after exposure to inactivated herpes simplex virus type 1.

Authors:  R Duff; F Rapp
Journal:  J Virol       Date:  1973-08       Impact factor: 5.103

9.  Replication of herpes simplex virus in mouse spleen cell cultures stimulated by lipopolysaccharide.

Authors:  H Kirchner; H M Hirt; C Kleinicke; K Munk
Journal:  J Immunol       Date:  1976-11       Impact factor: 5.422

10.  Genetic control of responses to bacterial lipopolysaccharides in mice. I. Evidence for a single gene that influences mitogenic and immunogenic respones to lipopolysaccharides.

Authors:  J Watson; R Riblet
Journal:  J Exp Med       Date:  1974-11-01       Impact factor: 14.307
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  10 in total

1.  Role of T lymphocytes in cellular immune responses during herpes simplex virus infection in humans.

Authors:  L Rasmussen; T C Merigan
Journal:  Proc Natl Acad Sci U S A       Date:  1978-08       Impact factor: 11.205

2.  Immune responses in mice against herpes simplex virus: mechanisms of protection against facial and ganglionic infections.

Authors:  H J Zweerink; D Martinez; R J Lynch; L W Stanton
Journal:  Infect Immun       Date:  1981-01       Impact factor: 3.441

3.  Influenza viruses are T cell-independent B cell mitogens.

Authors:  E M Anders; A A Scalzo; D O White
Journal:  J Virol       Date:  1984-06       Impact factor: 5.103

4.  Activation of mouse lymphocytes by vesicular stomatitis virus.

Authors:  G W Goodman-Snitkoff; J J McSharry
Journal:  J Virol       Date:  1980-09       Impact factor: 5.103

5.  Mitogenic activity of Sindbis virus and its isolated glycoproteins.

Authors:  G Goodman-Snitkoff; J J McSharry
Journal:  Infect Immun       Date:  1982-12       Impact factor: 3.441

6.  Sendai virus glycoproteins are T cell-dependent B cell mitogens.

Authors:  S Kizaka; G Goodman-Snitkoff; J J McSharry
Journal:  Infect Immun       Date:  1983-05       Impact factor: 3.441

7.  Molecular mimicry in virus infection: crossreaction of measles virus phosphoprotein or of herpes simplex virus protein with human intermediate filaments.

Authors:  R S Fujinami; M B Oldstone; Z Wroblewska; M E Frankel; H Koprowski
Journal:  Proc Natl Acad Sci U S A       Date:  1983-04       Impact factor: 11.205

8.  Distinct requirements for IL-6 in polyclonal and specific Ig production induced by microorganisms.

Authors:  D Markine-Goriaynoff; T D Nguyen; G Bigaignon; J Van Snick; J P Coutelier
Journal:  Int Immunol       Date:  2001-09       Impact factor: 4.823

9.  The glycoprotein isolated from vesicular stomatitis virus is mitogenic for mouse B lymphocytes.

Authors:  G Goodman-Snitkoff; R J Mannino; J J McSharry
Journal:  J Exp Med       Date:  1981-06-01       Impact factor: 14.307

Review 10.  Induction of interferon by virus glycoprotein(s) in lymphoid cells through interaction with the cellular receptors via lectin-like action: an alternative interferon induction mechanism.

Authors:  Y Ito
Journal:  Arch Virol       Date:  1994       Impact factor: 2.574
  10 in total

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